Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 14/20 | 0.34 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | GCK | P35557 | 2/20 | 0.33 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2180161 | 0.86 | NAMPT (0.37) | NAMPT | |
| SCHEMBL2179066 | 0.82 | EGLN2 (0.39) | NAMPTPIK3C3EGLN2EGLN1GCK | |
| SCHEMBL2178179 | 0.79 | ALDH1A1 (0.34) | NAMPTPIK3C3EGLN2EGLN1GCK | |
| SCHEMBL2178449 | 0.79 | PIK3C3 (0.37) | NAMPTPIK3C3GCKLNPEPCYP2C9 | |
| SCHEMBL2178618 | 0.78 | GCK (0.52) | EGLN2EGLN1GCKLNPEP | |
| SCHEMBL2038418 | 0.70 | KMT2A (0.38) | NAMPTGCK | |
| SCHEMBL2179866 | 0.69 | GSR (0.37) | NAMPTPIK3C3GCKCYP2C9 | |
| SCHEMBL2039421 | 0.68 | GCK (0.39) | GCK | |
| SCHEMBL2195760 | 0.66 | GCK (0.70) | GCK | |
| SCHEMBL2049518 | 0.66 | MEN1 (0.42) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011080755-A1 | FUSED NITROGEN HETEROCYCLIC COMPOUNDS, PROCESS OF PREPARATION AND USES THEREOF | ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) | 2011-07-07 | — | — | WO | claimed |
| WO-2011080755-A1 | FUSED NITROGEN HETEROCYCLIC COMPOUNDS, PROCESS OF PREPARATION AND USES THEREOF | ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) | 2011-07-07 | — | — | WO | disclosed |