Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 8/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.37 |
| ▸ | TACR3 | P29371 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22791325 | 0.87 | PTGDR2 (0.44) | MAPTPTGER1SCN9AALPLTACR3 | |
| SCHEMBL24127428 | 0.87 | SCN9A (0.38) | KMT2AMEN1MAPTPTGER1SCN9A | |
| SCHEMBL22791324 | 0.87 | SCN9A (0.38) | KMT2AMEN1MAPTPTGER1SCN9A | |
| SCHEMBL21786592 | 0.82 | PTGER1 (0.39) | KMT2ARAB9AMAPTPTGER1ALDH1A1 | |
| SCHEMBL24127176 | 0.80 | ALPL (0.58) | KMT2ANPC1RAB9AMAPTHTT | |
| SCHEMBL22791089 | 0.79 | MRGPRX4 (0.43) | PTGER1 | |
| SCHEMBL21786464 | 0.75 | ALPL (0.53) | KMT2ANPC1RAB9AMAPTPTGER1 | |
| SCHEMBL21786532 | 0.75 | ALPL (0.51) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL21786533 | 0.75 | ALPL (0.43) | ALPL | |
| SCHEMBL22790944 | 0.74 | SMPD1 (0.39) | PTGER1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020046382-A1 | SUBSTITUTED HETEROCYCLES AS C-MYC TARGETING AGENTS | NORTHWESTERN UNIVERSITY (US) | 2020-03-05 | — | — | WO | disclosed |