Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 2/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24595125 | 0.85 | PTGER4 (0.41) | KDM4EALDH1A1L3MBTL1EGLN2HTT | |
| SCHEMBL7213446 | 0.82 | HRH4 (0.37) | KDM4EALDH1A1L3MBTL1EGLN2HTT | |
| SCHEMBL19171969 | 0.81 | HTT (0.43) | KDM4EALDH1A1L3MBTL1HTTPTGER4 | |
| SCHEMBL29395259 | 0.80 | KDM4E (0.39) | KDM4EALDH1A1L3MBTL1EGLN2HTT | |
| SCHEMBL25238478 | 0.80 | KDM4E (0.39) | KDM4EALDH1A1L3MBTL1EGLN2HTT | |
| SCHEMBL25786530 | 0.80 | KDM4E (0.39) | KDM4EALDH1A1L3MBTL1EGLN2HTT | |
| SCHEMBL1425018 | 0.77 | EGLN2 (0.37) | KDM4EALDH1A1L3MBTL1EGLN2HTT | |
| SCHEMBL21786710 | 0.77 | EGLN2 (0.37) | KDM4EALDH1A1L3MBTL1EGLN2HTT | |
| SCHEMBL17883962 | 0.75 | GRM5 (0.43) | KDM4EALDH1A1L3MBTL1EGLN2HTT | |
| SCHEMBL30624366 | 0.72 | HTT (0.44) | KDM4EALDH1A1L3MBTL1EGLN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020046813-A1 | CD73 INHIBITORS | ARCUS BIOSCIENCES, INC. (US) | 2020-03-05 | — | — | WO | disclosed |