Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HPGDS | O60760 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7219002 | 0.86 | ALDH1A1 (0.38) | HTTPTGER4HPGDSMAPK1KDM4E | |
| SCHEMBL21786716 | 0.82 | KDM4E (0.38) | HTTPTGER4MEN1KMT2AHPGDS | |
| SCHEMBL19171969 | 0.81 | HTT (0.43) | HRH4HTTPTGER4MEN1KMT2A | |
| SCHEMBL7219758 | 0.78 | EGLN2 (0.40) | HTTPTGER4MEN1KMT2AHPGDS | |
| SCHEMBL21107375 | 0.77 | KDM4E (0.44) | HRH4HTTPTGER4HPGDSKDM4E | |
| SCHEMBL13838604 | 0.73 | PDE10A (0.35) | KDM4EALDH1A1PDE10A | |
| SCHEMBL25284464 | 0.72 | HPGDS (0.36) | HTTHPGDSMAPK1KDM4EALDH1A1 | |
| SCHEMBL29392663 | 0.72 | HPGDS (0.36) | HTTHPGDSMAPK1KDM4EALDH1A1 | |
| SCHEMBL19171823 | 0.71 | HTT (0.41) | HTTPTGER4MEN1KMT2AKDM4E | |
| SCHEMBL7309110 | 0.71 | TSHR (0.41) | HTTPTGER4KDM4EALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6603007-B1 | Intermediates in the fields of pharmaceuticals, agrichemicals, ligands, silver halide photosensitive materials, liquid crystals, surfactants, electrophotography and organic electroluminescence | SANKIO CHEMICAL CO., LTD. (JP) | 2003-08-05 | — | — | US | disclosed |
| EP-1231207-A1 | NOVEL BIPYRIDYL DERIVATIVES | Sankio Chemical Co., Ltd. (JP) | 2002-08-14 | — | — | EP | disclosed |