Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.31 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2178963 | 0.85 | SCD (0.39) | SCDMAPTEGLN1 | |
| SCHEMBL2177226 | 0.85 | MGAM (0.32) | SCDEGLN1NR1I3 | |
| SCHEMBL12408991 | 0.80 | SCD (0.42) | SCDMAPTEGLN1 | |
| SCHEMBL2176716 | 0.80 | SCD (0.37) | SCDMAPTEGLN1 | |
| SCHEMBL2179985 | 0.78 | MAPT (0.39) | SCDMAPTEGLN1NR1I3 | |
| SCHEMBL12408989 | 0.73 | MAPT (0.40) | SCDMAPTEGLN1NR1I3 | |
| SCHEMBL2178356 | 0.70 | EGLN1 (0.36) | SCDEGLN1 | |
| SCHEMBL2181543 | 0.69 | ROCK2 (0.37) | EGLN1NR1I3 | |
| SCHEMBL2179568 | 0.68 | EGLN1 (0.35) | SCDEGLN1 | |
| SCHEMBL1990584 | 0.68 | CD74 (0.41) | SCDMAPTEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2350097-A1 | HETEROAROMATIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | Merck Frosst Canada Ltd. (CA) | 2011-08-03 | — | — | EP | disclosed |
| US-20110166152-A1 | HETEROAROMATIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | MERCK FROSST CANADA LTD. (CA) | 2011-07-07 | — | — | US | disclosed |
| WO-2010037225-A1 | HETEROAROMATIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | MERCK FROSST CANADA LTD. (CA) | 2010-04-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110166152-A1 | HETEROAROMATIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | SCD, SCD5, CPT1A | SCD 1/4885MAPT 2772/4885EGLN1 1112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.