Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TNKS | O95271 | 1/20 | 0.31 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21767493 | 0.90 | KDM4E (0.34) | KDM4EALDH1A1HPGDNPC1CYP2C19 | |
| SCHEMBL21777972 | 0.70 | KDM4E (0.34) | KDM4EALDH1A1HPGDNPC1CYP2C19 | |
| SCHEMBL21777971 | 0.67 | KDM4E (0.41) | KDM4EALDH1A1HPGDHTTHSD17B10 | |
| SCHEMBL25976562 | 0.58 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL10483656 | 0.58 | TSHR (0.51) | ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL14168777 | 0.57 | CHRM5 (0.36) | KDM4ECYP2C19MAPTMEN1KMT2A | |
| SCHEMBL21787392 | 0.57 | TNKS (0.35) | NPC1RAB9ASMN1; SMN2TNKSTNKS2 | |
| SCHEMBL19822059 | 0.56 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL20698732 | 0.56 | — | — | |
| SCHEMBL26413809 | 0.55 | ALDH1A1 (0.31) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020047207-A1 | INHIBITORS OF (ALPHA-V)(BETA-6) INTEGRIN | MORPHIC THERAPEUTICS, INC. (US) | 2020-03-05 | — | — | WO | disclosed |