Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 3/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.35 |
| ▸ | RAB7A | P51149 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21777996 | 0.91 | MTNR1A (0.34) | MTNR1AMTNR1BRORCSMN1; SMN2NPC1 | |
| SCHEMBL21767529 | 0.90 | MTNR1A (0.35) | MTNR1AMTNR1BRORCSMN1; SMN2NPC1 | |
| SCHEMBL30493364 | 0.90 | MTNR1A (0.35) | MTNR1AMTNR1BRORCSMN1; SMN2NPC1 | |
| SCHEMBL21777227 | 0.73 | MTNR1A (0.40) | MTNR1AMTNR1BRORC | |
| SCHEMBL27813798 | 0.72 | PNMT (0.50) | MTNR1AMTNR1BSMN1; SMN2NPC1RAB9A | |
| SCHEMBL31583065 | 0.72 | MTNR1A (0.38) | MTNR1AMTNR1BRORCSMN1; SMN2NPC1 | |
| SCHEMBL9863289 | 0.70 | MTNR1A (0.52) | MTNR1AMTNR1BRORCNPC1RAB9A | |
| SCHEMBL15042391 | 0.70 | DDB1 (0.50) | L3MBTL1NAMPT | |
| SCHEMBL15068402 | 0.70 | MTNR1A (0.39) | MTNR1AMTNR1BRORCL3MBTL1 | |
| SCHEMBL20424706 | 0.68 | XIAP (0.38) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020047207-A1 | INHIBITORS OF (ALPHA-V)(BETA-6) INTEGRIN | MORPHIC THERAPEUTICS, INC. (US) | 2020-03-05 | — | — | WO | disclosed |