SCHEMBL21787722

SCHEMBL21787722

SCCc1ncc(-c2ccccc2)cn1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.50
NPC1 O15118 2/20 0.50
NFKB1 P19838 2/20 0.50
NFKB2 Q00653 2/20 0.50
RELA Q04206 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
MAPT P10636 1/20 0.41
ALDH1A1 P00352 1/20 0.38
ACHE P22303 1/20 0.37
USP7 Q93009 1/20 0.35
FOLH1 Q04609 1/20 0.35
MAP4K4 O95819 1/20 0.35
GSK3B P49841 1/20 0.35
NOTUM Q6P988 1/20 0.34
AXL P30530 1/20 0.34
CDK8 P49336 1/20 0.34
HIF1A Q16665 1/20 0.34
CES1 P23141 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28789382 0.79 RAB9A (0.56) RAB9ANPC1NFKB1NFKB2RELA
SCHEMBL21787590 0.76 CYP11B2 (0.42) ALDH1A1MAP4K4
SCHEMBL5202739 0.75 RAB9A (0.45) RAB9ANPC1NFKB1NFKB2RELA
SCHEMBL9171005 0.74 RAB9A (0.54) RAB9ANPC1NFKB1NFKB2RELA
SCHEMBL12092479 0.74 RAB9A (0.54) RAB9ANPC1NFKB1NFKB2RELA
SCHEMBL9582152 0.74 RAB9A (0.54) RAB9ANPC1NFKB1NFKB2RELA
SCHEMBL1509570 0.74 RAB9A (0.54) RAB9ANPC1NFKB1NFKB2RELA
SCHEMBL16815729 0.74 RAB9A (0.54) RAB9ANPC1NFKB1NFKB2RELA
SCHEMBL19060925 0.70 RAB9A (0.61) RAB9ANPC1NFKB1NFKB2RELA
SCHEMBL12089070 0.69 RAB9A (0.48) RAB9ANPC1NFKB1NFKB2RELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11171300-B2 Quantum dot light emitting diode, method for fabricating the same, and display device BOE TECHNOLOGY GROUP CO., LTD. (CN) 2021-11-09 US disclosed
US-20200075877-A1 QUANTUM DOT LIGHT EMITTING DIODE, METHOD FOR FABRICATING THE SAME, AND DISPLAY DEVICE BOE TECHNOLOGY GROUP CO., LTD. (CN) 2020-03-05 US disclosed