Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1936673 | 0.81 | ALDH1A1 (0.48) | ALDH1A1KDM4EGAAHPGDHTT | |
| SCHEMBL29072286 | 0.75 | ALDH1A1 (0.42) | ALDH1A1KDM4EHPGDHTTLMNA | |
| SCHEMBL21776796 | 0.74 | DAO (0.53) | ALDH1A1KDM4EABL1GAAHPGD | |
| SCHEMBL21787713 | 0.72 | CA12 (0.41) | ALDH1A1KDM4EABL1GAAHPGD | |
| SCHEMBL21788045 | 0.72 | ABL1 (0.44) | ALDH1A1KDM4EABL1GAAHPGD | |
| SCHEMBL15784497 | 0.71 | HSD17B10 (0.60) | ALDH1A1KDM4ELMNAPOLBHSD17B10 | |
| SCHEMBL21776750 | 0.71 | ABL1 (0.39) | ALDH1A1KDM4EABL1GAAHPGD | |
| SCHEMBL19506015 | 0.71 | CA1 (0.39) | ALDH1A1KDM4EABL1GAAHPGD | |
| SCHEMBL19506014 | 0.70 | ALDH1A1 (0.51) | ALDH1A1ABL1GAAHTTLMNA | |
| SCHEMBL74642 | 0.68 | PDE4A (0.44) | ALDH1A1KDM4EHPGDLMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210346336-A1 | FURAN DERIVATIVES AS BROMODOMAIN INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2021-11-11 | — | — | US | disclosed |
| WO-2020043821-A1 | FURAN DERIVATIVES AS BROMODOMAIN INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2020-03-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210346336-A1 | FURAN DERIVATIVES AS BROMODOMAIN INHIBITORS | BRD4, BRD3, BRDT | ALDH1A1 2126/4885KDM4E 820/4885ABL1 358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.