Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | NQO2 | P16083 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21776796 | 0.84 | DAO (0.53) | ABL1GAAALDH1A1KDM4EPOLB | |
| SCHEMBL21776750 | 0.81 | ABL1 (0.39) | ABL1GAAALDH1A1KDM4EPOLB | |
| SCHEMBL19506014 | 0.73 | ALDH1A1 (0.51) | ABL1GAAALDH1A1TSHRLMNA | |
| SCHEMBL21787713 | 0.72 | CA12 (0.41) | ABL1GAAALDH1A1KDM4EPOLB | |
| SCHEMBL21787787 | 0.72 | ALDH1A1 (0.47) | ABL1GAAALDH1A1KDM4EPOLB | |
| SCHEMBL19506015 | 0.71 | CA1 (0.39) | ABL1GAAALDH1A1KDM4EHPGD | |
| SCHEMBL31215708 | 0.71 | KDM4E (0.49) | ABL1GAANQO2ALDH1A1KDM4E | |
| SCHEMBL31215545 | 0.71 | NPC1 (0.42) | GAAALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL19258586 | 0.68 | HTT (0.58) | GAAALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL31215837 | 0.68 | KDM4E (0.37) | GAAALDH1A1KDM4EPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020043821-A1 | FURAN DERIVATIVES AS BROMODOMAIN INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2020-03-05 | — | — | WO | disclosed |