Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HPD | P32754 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12157011 | 0.94 | ADORA2B (0.41) | ADORA2BKDM4EALDH1A1MAPTHCRTR1 | |
| SCHEMBL1318483 | 0.87 | ALDH1A1 (0.42) | ADORA2BKDM4EALDH1A1MAPTHCRTR1 | |
| SCHEMBL21500472 | 0.81 | ALDH1A1 (0.41) | ADORA2BKDM4EALDH1A1MAPTHCRTR1 | |
| SCHEMBL22692858 | 0.79 | ADORA2B (0.34) | ADORA2B | |
| SCHEMBL2757599 | 0.76 | ADORA2B (0.38) | ADORA2BKDM4EALDH1A1MAPTHCRTR1 | |
| SCHEMBL25061686 | 0.74 | ALDH1A1 (0.44) | KDM4EALDH1A1MAPTHCRTR1GAA | |
| SCHEMBL22374265 | 0.74 | KDM4E (0.34) | KDM4EALDH1A1MAPTHCRTR1GAA | |
| SCHEMBL21082580 | 0.74 | KDM4E (0.34) | KDM4EALDH1A1MAPTHCRTR1GAA | |
| SCHEMBL25061425 | 0.72 | ALDH1A1 (0.39) | ADORA2BKDM4EALDH1A1MAPTHCRTR1 | |
| SCHEMBL11682290 | 0.72 | ALDH1A1 (0.44) | ADORA2BKDM4EALDH1A1MAPTHCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11667823-B2 | Urethane adhesive composition | SIKA HAMATITE CO., LTD. (JP) | 2023-06-06 | — | — | US | disclosed |
| US-20230122028-A1 | COATING COMPOSITION | COVESTRO (NETHERLANDS) B.V. (NL) | 2023-04-20 | — | — | US | disclosed |
| US-20210147484-A1 | BICYCLIC PEPTIDE LIGANDS AND USES THEREOF | BICYCLETX LIMITED (GB) | 2021-05-20 | — | — | US | disclosed |
| US-20200069814-A1 | CONJUGATION OF A CYTOTOXIC DRUG WITH BIS-LINKAGE | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2020-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200069814-A1 | CONJUGATION OF A CYTOTOXIC DRUG WITH BIS-LINKAGE | CD4, MCL1, CCNB1 | ADORA2B 3121/4885KDM4E 3038/4885ALDH1A1 1130/4885 |
| US-20210147484-A1 | BICYCLIC PEPTIDE LIGANDS AND USES THEREOF | VIP, NGLY1, BID | ADORA2B 3623/4885KDM4E 4848/4885ALDH1A1 4861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.