Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 1/20 | 0.47 |
| ▸ | STING1 | Q86WV6 | 14/20 | 0.39 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21789703 | 0.83 | STING1 (0.52) | ENPP1STING1TBK1 | |
| SCHEMBL22150032 | 0.76 | RAB9A (0.57) | NPC1RAB9AIRAK4 | |
| SCHEMBL29791276 | 0.74 | STING1 (0.52) | ENPP1STING1 | |
| SCHEMBL31066898 | 0.74 | STING1 (0.52) | ENPP1STING1 | |
| SCHEMBL25831201 | 0.73 | STING1 (0.63) | ENPP1STING1 | |
| SCHEMBL29675240 | 0.73 | STING1 (0.63) | ENPP1STING1 | |
| Hydrochloric Acid SCHEMBL31066892 | 0.72 | STING1 (0.62) | ENPP1STING1 | |
| SCHEMBL28720810 | 0.72 | STING1 (0.60) | ENPP1STING1TBK1 | |
| SCHEMBL30084070 | 0.72 | STING1 (0.58) | ENPP1STING1TBK1 | |
| SCHEMBL29626030 | 0.72 | STING1 (0.60) | ENPP1STING1TBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020042995-A1 | HIGHLY ACTIVE STING PROTEIN AGONIST COMPOUND | 杭州阿诺生物医药科技有限公司 | 2020-03-05 | — | — | WO | disclosed |