Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 19/20 | 0.52 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.52 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29675240 | 0.87 | STING1 (0.63) | STING1ENPP1 | |
| SCHEMBL25831201 | 0.87 | STING1 (0.63) | STING1ENPP1 | |
| Hydrochloric Acid SCHEMBL31066892 | 0.87 | STING1 (0.62) | STING1ENPP1 | |
| SCHEMBL29899007 | 0.84 | STING1 (0.65) | STING1 | |
| SCHEMBL21789649 | 0.83 | ENPP1 (0.47) | STING1TBK1ENPP1 | |
| SCHEMBL29626030 | 0.83 | STING1 (0.60) | STING1TBK1ENPP1 | |
| SCHEMBL28720810 | 0.83 | STING1 (0.60) | STING1TBK1ENPP1 | |
| SCHEMBL29686555 | 0.83 | STING1 (0.53) | STING1TBK1 | |
| SCHEMBL30803059 | 0.82 | STING1 (0.57) | STING1ENPP1 | |
| SCHEMBL30084070 | 0.81 | STING1 (0.58) | STING1TBK1ENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3848366-A1 | HIGHLY ACTIVE STING PROTEIN AGONIST COMPOUND | Adlai Nortye Biopharma Co., Ltd. (CN) | 2021-07-14 | — | — | EP | disclosed |
| WO-2020042995-A1 | HIGHLY ACTIVE STING PROTEIN AGONIST COMPOUND | 杭州阿诺生物医药科技有限公司 | 2020-03-05 | — | — | WO | disclosed |