Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | FABP6 | P51161 | 2/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | QTRT1 | Q9BXR0 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 6/20 | 0.34 |
| ▸ | TYMS | P04818 | 1/20 | 0.34 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.33 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.33 |
| ▸ | PNP | P00491 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22136289 | 0.82 | FABP6 (0.42) | PLAUFABP6ABL1CHEK2TYMS | |
| SCHEMBL21789936 | 0.78 | PTPN11 (0.33) | PTPN11LCKCHEK2CYP3A4 | |
| SCHEMBL1581142 | 0.72 | ERCC1 (0.52) | CHEK2 | |
| SCHEMBL30605006 | 0.71 | PIM1 (0.38) | PTPN11LCKBLM | |
| SCHEMBL22121440 | 0.71 | FABP6 (0.51) | PLAUFABP6ABL1CHEK2PKN1 | |
| SCHEMBL12685844 | 0.68 | ABL1 (0.68) | PLAUFABP6ABL1CHEK2PKN1 | |
| SCHEMBL21708401 | 0.66 | ALDH1A1 (0.48) | PLAUQTRT1TYMS | |
| SCHEMBL2139 | 0.65 | KDM4E (0.59) | PTPN11LCKBLM | |
| Carbamic Acid SCHEMBL6315472 | 0.65 | PLAU (0.39) | PLAUFABP6ABL1QTRT1TYMS | |
| SCHEMBL14395470 | 0.64 | KDM4E (0.49) | PNPCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020042995-A1 | HIGHLY ACTIVE STING PROTEIN AGONIST COMPOUND | 杭州阿诺生物医药科技有限公司 | 2020-03-05 | — | — | WO | disclosed |