Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 2/20 | 0.33 |
| ▸ | NNMT | P40261 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 4/20 | 0.32 |
| ▸ | ALPL | P05186 | 2/20 | 0.32 |
| ▸ | ALPG | P10696 | 2/20 | 0.32 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.31 |
| ▸ | TUBB | P07437 | 1/20 | 0.31 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.31 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.31 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.31 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.31 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21789938 | 0.78 | PLAU (0.38) | PTPN11LCKCHEK2CYP3A4 | |
| SCHEMBL21789703 | 0.73 | STING1 (0.52) | — | |
| SCHEMBL1581142 | 0.68 | ERCC1 (0.52) | CHEK2KMT2A | |
| SCHEMBL30605006 | 0.67 | PIM1 (0.38) | PTPN11NNMTLCK | |
| SCHEMBL22136289 | 0.65 | FABP6 (0.42) | CHEK2KMT2A | |
| SCHEMBL8537859 | 0.63 | KDM4E (0.39) | PTPN11NNMTLCKALPLALPG | |
| SCHEMBL13085935 | 0.63 | AURKA (0.47) | CHEK2KMT2A | |
| SCHEMBL21783726 | 0.63 | POLB (0.39) | KMT2A | |
| Carbamic Acid SCHEMBL6315744 | 0.62 | HRH4 (0.49) | CYP3A4KMT2A | |
| SCHEMBL2671396 | 0.62 | KDM4E (0.49) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020042995-A1 | HIGHLY ACTIVE STING PROTEIN AGONIST COMPOUND | 杭州阿诺生物医药科技有限公司 | 2020-03-05 | — | — | WO | disclosed |