Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL62097 | 0.80 | — | — | |
| SCHEMBL18993461 | 0.76 | TSHR (0.43) | RIPK1 | |
| SCHEMBL19118274 | 0.76 | MEN1 (0.42) | RIPK1 | |
| SCHEMBL276972 | 0.76 | — | — | |
| SCHEMBL26976805 | 0.74 | RIPK1 (0.40) | RIPK1 | |
| SCHEMBL18722219 | 0.74 | RIPK1 (0.35) | RIPK1 | |
| SCHEMBL18974140 | 0.74 | RIPK1 (0.35) | RIPK1 | |
| SCHEMBL10786397 | 0.74 | RIPK1 (0.35) | RIPK1 | |
| SCHEMBL598284 | 0.72 | RIPK1 (0.38) | RIPK1 | |
| SCHEMBL23349147 | 0.72 | LMNA (0.62) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200071308-A1 | Benzene, Pyridine, and Pyridazine Derivatives | ESANEX INC (US) | 2020-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200071308-A1 | Benzene, Pyridine, and Pyridazine Derivatives | CDK4, P2RX4, MKI67 | RIPK1 3444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.