Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 10/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ADH1B | P00325 | 1/20 | 0.38 |
| ▸ | ADH1C | P00326 | 1/20 | 0.38 |
| ▸ | ADH1A | P07327 | 1/20 | 0.38 |
| ▸ | ADH4 | P08319 | 1/20 | 0.38 |
| ▸ | ADH7 | P40394 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 2/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18482260 | 0.98 | EPHX1 (0.44) | EPHX1TSHRALDH1A1ADH1BADH1C | |
| SCHEMBL28182999 | 0.98 | EPHX1 (0.44) | EPHX1TSHRALDH1A1ADH1BADH1C | |
| SCHEMBL20643823 | 0.98 | EPHX1 (0.44) | EPHX1TSHRALDH1A1ADH1BADH1C | |
| SCHEMBL19352948 | 0.93 | EPHX1 (0.39) | EPHX1TSHRALDH1A1ADH1BADH1C | |
| SCHEMBL19242564 | 0.93 | TSHR (0.36) | EPHX1TSHRALDH1A1ADH1BADH1C | |
| SCHEMBL21790560 | 0.90 | LMNA (0.48) | EPHX1TSHRALDH1A1 | |
| SCHEMBL22851010 | 0.90 | DNM1 (0.48) | EPHX1TSHRALDH1A1FDPS | |
| SCHEMBL23808925 | 0.89 | EPHX1 (0.41) | EPHX1TSHRALDH1A1ADH1BADH1C | |
| SCHEMBL18525926 | 0.88 | EPHX1 (0.39) | EPHX1TSHRALDH1A1ADH1BADH1C | |
| SCHEMBL24045162 | 0.88 | EPHX1 (0.39) | EPHX1TSHRALDH1A1ADH1BADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200071308-A1 | Benzene, Pyridine, and Pyridazine Derivatives | ESANEX INC (US) | 2020-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200071308-A1 | Benzene, Pyridine, and Pyridazine Derivatives | CDK4, P2RX4, MKI67 | EPHX1 421/4885TSHR 1413/4885ALDH1A1 1049/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.