SCHEMBL21790491

SCHEMBL21790491

O=C(Oc1ccccc1)Oc1ccc(-c2ccc(O)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP3 P08254 1/20 0.54
BCL2L1 Q07817 1/20 0.54
LTA4H P09960 1/20 0.54
NR1H2 P55055 1/20 0.54
BAX Q07812 1/20 0.54
KMT2A Q03164 4/20 0.52
MEN1 O00255 3/20 0.52
MAPT P10636 3/20 0.52
LMNA P02545 2/20 0.52
RAB9A P51151 1/20 0.52
ESR2 Q92731 3/20 0.47
P4HB P07237 1/20 0.46
GAA P10253 1/20 0.46
HTT P42858 1/20 0.46
NPSR1 Q6W5P4 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
HSD17B10 Q99714 2/20 0.44
HPGD P15428 1/20 0.44
ALOX15 P16050 1/20 0.44
ESR1 P03372 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21790493 1.00 MMP3 (0.54) MMP3BCL2L1LTA4HNR1H2BAX
SCHEMBL10707250 0.94 LTA4H (0.60) LTA4HNR1H2BAXKMT2AMEN1
SCHEMBL8059094 0.92 ESR2 (0.54) MMP3BCL2L1KMT2AMEN1MAPT
SCHEMBL21790492 0.92 KMT2A (0.50) KMT2AMEN1MAPTLMNARAB9A
Hydroquinone SCHEMBL9277105 0.92 LTA4H (0.56) MMP3BCL2L1LTA4HNR1H2BAX
SCHEMBL29044797 0.92 ESR2 (0.54) MMP3BCL2L1KMT2AMEN1MAPT
SCHEMBL246849 0.90 KMT2A (0.53) KMT2AMEN1MAPTLMNARAB9A
Phenol SCHEMBL1893975 0.87 TDP1 (0.52) LTA4HNR1H2BAXKMT2AMEN1
SCHEMBL233643 0.87 KMT2A (0.55) MMP3KMT2AMEN1MAPTLMNA
Phenol SCHEMBL27663623 0.87 TDP1 (0.52) LTA4HNR1H2BAXKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11130840-B2 Aromatic polycarbonate oligomer solid HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2021-09-28 US disclosed
US-20200071460-A1 AROMATIC POLYCARBONATE OLIGOMER SOLID HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2020-03-05 US disclosed