Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19353173 | 0.88 | SMYD3 (0.33) | SMYD3CNR2 | |
| SCHEMBL21790581 | 0.76 | NPC1 (0.40) | CNR2 | |
| SCHEMBL14984921 | 0.68 | — | — | |
| SCHEMBL21017126 | 0.67 | ALOX12 (0.48) | TLR8 | |
| SCHEMBL19852711 | 0.67 | ALOX12 (0.48) | TLR8 | |
| SCHEMBL23768097 | 0.67 | ALOX12 (0.48) | TLR8 | |
| SCHEMBL25767654 | 0.67 | KDM4E (0.41) | TLR8CNR2 | |
| SCHEMBL23768191 | 0.66 | TLR8 (0.41) | TLR8CNR2 | |
| SCHEMBL23768209 | 0.66 | HTT (0.38) | TLR8CNR2 | |
| SCHEMBL23697490 | 0.66 | ALOX12 (0.47) | TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200071308-A1 | Benzene, Pyridine, and Pyridazine Derivatives | ESANEX INC (US) | 2020-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200071308-A1 | Benzene, Pyridine, and Pyridazine Derivatives | CDK4, P2RX4, MKI67 | SMYD3 3105/4885TLR8 2517/4885CNR2 222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.