Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 17/20 | 0.57 |
| ▸ | CRBN | Q96SW2 | 17/20 | 0.57 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | IL1B | P01584 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26517252 | 0.87 | DDB1 (0.56) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL21792468 | 0.85 | CRBN (0.50) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL21062845 | 0.84 | CRBN (0.60) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL32679446 | 0.84 | CRBN (0.60) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL28704521 | 0.81 | DDB1 (0.60) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL21615149 | 0.81 | DDB1 (0.57) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL19604114 | 0.79 | DDB1 (0.50) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL29257433 | 0.79 | DDB1 (0.50) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL24421051 | 0.77 | DDB1 (0.47) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL29614631 | 0.77 | DDB1 (0.47) | DDB1CRBNIKZF3TNFIL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11021457-B2 | Class of isoindolone-imide ring-1,3-dione-2-ene compounds, composition and use thereof | Wigen Biomedicine Technology (shanghai) Co., Ltd. (CN) | 2021-06-01 | — | — | US | disclosed |
| US-20200071291-A1 | A CLASS OF ISOINDOLONE-IMIDE RING-1,3-DIONE-2-ENE COMPOUNDS, COMPOSITION AND USE THEREOF | Wigen Biomedicine Technology (shanghai) Co., Ltd. (CN) | 2020-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200071291-A1 | A CLASS OF ISOINDOLONE-IMIDE RING-1,3-DIONE-2-ENE COMPOUNDS, COMPOSITION AND USE THEREOF | ATG7, MLST8, BECN1 | DDB1 1836/4885CRBN 846/4885IKZF3 889/4885 |
| US-11021457-B2 | Class of isoindolone-imide ring-1,3-dione-2-ene compounds, composition and use thereof | ATG7, MLST8, BECN1 | DDB1 1595/4885CRBN 978/4885IKZF3 701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.