SCHEMBL32679446

SCHEMBL32679446

CN1C(=O)CCC(N2C(=O)c3cccc(F)c3C2=O)C1=O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 12/20 0.60
DDB1 Q16531 11/20 0.60
IKZF3 Q9UKT9 2/20 0.43
TNF P01375 1/20 0.43
IL1B P01584 1/20 0.43
TBXA2R P21731 1/20 0.43
IKZF1 Q13422 1/20 0.43
ADRA1D P25100 1/20 0.40
ADRA1A P35348 1/20 0.40
ADRA1B P35368 1/20 0.40
STAT3 P40763 1/20 0.39
ALDH1A1 P00352 1/20 0.39
CHRM2 P08172 1/20 0.39
OPRM1 P35372 1/20 0.39
CYP1A2 P05177 1/20 0.39
TSHR P16473 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
HPGDS O60760 1/20 0.38
MIF P14174 1/20 0.38
HTR2B P41595 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21062845 1.00 CRBN (0.60) CRBNDDB1IKZF3TNFIL1B
SCHEMBL9988681 0.86 DDB1 (0.60) CRBNDDB1IKZF3TNFIL1B
SCHEMBL22940384 0.86 CRBN (0.62) CRBNDDB1IKZF3TNFIL1B
SCHEMBL21196697 0.85 DDB1 (0.60) CRBNDDB1IKZF3TNFIL1B
SCHEMBL28704521 0.85 DDB1 (0.60) CRBNDDB1IKZF3TNFIL1B
SCHEMBL21792467 0.84 DDB1 (0.57) CRBNDDB1IKZF3TNFIL1B
SCHEMBL21615149 0.84 DDB1 (0.57) CRBNDDB1IKZF3TNFIL1B
SCHEMBL26753159 0.84 CRBN (0.42) CRBNDDB1IKZF3TNFIL1B
SCHEMBL12041893 0.84 CRBN (0.53) CRBNDDB1IKZF3TNFIL1B
SCHEMBL845548 0.83 CRBN (0.54) CRBNDDB1IKZF3TNFIL1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121574723-A Application of pomalidomide and various derivatives thereof as electrochemiluminescence probes 厦门医学院 2026-02-27 CN disclosed