⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10752183 | 0.75 | CYP1A2 (0.32) | — | |
| SCHEMBL6651030 | 0.73 | CYP1A2 (0.31) | — | |
| SCHEMBL21681592 | 0.72 | TYR (0.45) | — | |
| SCHEMBL13488529 | 0.72 | TDP2 (0.39) | — | |
| Phosphine SCHEMBL6882504 | 0.72 | CYP1A2 (0.30) | — | |
| Ammonia Solution, Strong SCHEMBL622795 | 0.72 | PON1 (0.31) | — | |
| Ammonia Solution, Strong SCHEMBL20163272 | 0.71 | TYR (0.44) | — | |
| Ammonia Solution, Strong SCHEMBL7162840 | 0.71 | TYR (0.44) | — | |
| Ammonia Solution, Strong SCHEMBL20163253 | 0.71 | TYR (0.44) | — | |
| SCHEMBL1045173 | 0.69 | TRPA1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2751577-B1 | A method of manufacturing a sterilized optical analyte sensor | MEDTRONIC MINIMED INC (US) | 2019-04-17 | — | — | EP | disclosed |
| EP-2989975-B1 | OPTICAL SYSTEMS AND METHODS FOR RATIONMETRIC MEASUREMENT OF BLOOD GLUCOSE CONCENTRATION | MEDTRONIC MINIMED INC (US) | 2018-06-13 | — | — | EP | disclosed |
| US-9839378-B2 | Optical systems and methods for ratiometric measurement of blood glucose concentration | MEDTRONIC MINIMED, INC. (US) | 2017-12-12 | — | — | US | disclosed |
| US-9757057-B2 | Dry insertion and one-point in vivo calibration of an optical analyte sensor | MEDTRONIC MINIMED, INC. (US) | 2017-09-12 | — | — | US | disclosed |
| US-9693720-B2 | Equilibrium non-consuming fluorescence sensor for real time intravascular glucose measurement | MEDTRONIC MINIMED, INC. (US) | 2017-07-04 | — | — | US | disclosed |
| EP-2989975-A1 | OPTICAL SYSTEMS AND METHODS FOR RATIONMETRIC MEASUREMENT OF BLOOD GLUCOSE CONCENTRATION | Medtronic MiniMed, Inc. (US) | 2016-03-02 | — | — | EP | disclosed |
| EP-2916722-A1 | DRY INSERTION AND ONE-POINT IN VIVO CALIBRATION OF AN OPTICAL ANALYTE SENSOR | Medtronic MiniMed, Inc. (US) | 2015-09-16 | — | — | EP | disclosed |
| US-20150080685-A1 | EQUILIBRIUM NON-CONSUMING FLUORESCENCE SENSOR FOR REAL TIME INTRAVASCULAR GLUCOSE MEASUREMENT | MEDTRONIC MINIMED, INC. (US) | 2015-03-19 | — | — | US | disclosed |
| US-8979790-B2 | Use of an equilibrium sensor to monitor glucose concentration | MEDTRONIC MINIMED, INC. (US) | 2015-03-17 | — | — | US | disclosed |
| US-8983565-B2 | Optical determination of pH and glucose | MEDTRONIC MINIMED, INC. (US) | 2015-03-17 | — | — | US | disclosed |
| WO-2007067743-A2 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS-II | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-06-14 | — | — | WO | disclosed |
| US-20060083688-A1 | Optical determination of glucose utilizing boronic acid adducts | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2006-04-20 | — | — | US | disclosed |
| US-20040028612-A1 | Optical determination of glucose utilizing boronic acid adducts | REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | 2004-02-12 | — | — | US | disclosed |
| US-6653141-B2 | In vitro detection of polyhydroxyl-substituted organic molecules; obtain sample, incubate in fluorescent dye exposure to excitation light detect and measure signal | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-11-25 | — | — | US | disclosed |
| US-6627177-B2 | Obtaining flurorophore dye which is compatible with the analyte solution; combining withboronic acid-containing quencher molecule; contacting with excitation light source coupled with a detector; producing signal; quantification | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-09-30 | — | — | US | disclosed |
| EP-1340076-A2 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | The Regents of the University of California (US) | 2003-09-03 | — | — | EP | disclosed |
| WO-2002046752-A9 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | UNIV CALIFORNIA (US) | 2002-08-29 | — | — | WO | disclosed |
| US-20020106326-A1 | Polyhydroxyl-substituted organic molecule sensing optical in vivo method utilizing a boronic acid adduct and the device thereof | CALIFORNIA, UNIVERSITY OF THE REGENTS OF THE | 2002-08-08 | — | — | US | disclosed |
| US-20020106810-A1 | Polyhydroxyl-substituted organic molecule sensing optical in vitro method utilizing a boronic acid adduct and the device thereof | REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | 2002-08-08 | — | — | US | disclosed |
| WO-2002046752-A2 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2002-06-13 | — | — | WO | disclosed |