Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | APP | P05067 | 3/20 | 0.56 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30107670 | 0.90 | NPC1 (0.68) | TLR9NPC1RAB9ASMN1; SMN2APP | |
| SCHEMBL15850502 | 0.90 | NPC1 (0.68) | TLR9NPC1RAB9ASMN1; SMN2APP | |
| SCHEMBL21777625 | 0.86 | NPC1 (0.68) | TLR9NPC1RAB9ASMN1; SMN2FGFR3 | |
| SCHEMBL28853094 | 0.85 | TLR9 (0.81) | TLR9NPC1RAB9ASMN1; SMN2APP | |
| SCHEMBL21793877 | 0.84 | NPC1 (0.57) | TLR9NPC1RAB9ASMN1; SMN2APP | |
| SCHEMBL30723189 | 0.84 | NPC1 (0.57) | TLR9NPC1RAB9ASMN1; SMN2APP | |
| SCHEMBL27323740 | 0.83 | BCHE (0.63) | TLR9NPC1RAB9ASMN1; SMN2FGFR3 | |
| SCHEMBL30665751 | 0.83 | BCHE (0.63) | TLR9NPC1RAB9ASMN1; SMN2FGFR3 | |
| SCHEMBL31503559 | 0.82 | SMN1; SMN2 (0.67) | TLR9NPC1RAB9ASMN1; SMN2FGFR3 | |
| SCHEMBL28534153 | 0.82 | SMN1; SMN2 (0.67) | TLR9NPC1RAB9ASMN1; SMN2FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020046335-A1 | COMPOUNDS USEFUL AS CHAPERONE-MEDIATED AUTOPHAGY MODULATORS | ALBERT EINSTEIN COLLEGE OF MEDICINE, INC. (US) | 2020-03-05 | — | — | WO | disclosed |