SCHEMBL28534153

SCHEMBL28534153

Clc1ccc2nc(-c3ccccc3)cnc2c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.67
NPC1 O15118 3/20 0.67
RAB9A P51151 3/20 0.67
TLR9 Q9NR96 1/20 0.66
KDR P35968 2/20 0.60
PDGFRB P09619 1/20 0.60
FLT3 P36888 1/20 0.60
ALDH1A1 P00352 1/20 0.55
GLA P06280 1/20 0.55
GAA P10253 1/20 0.55
MAPT P10636 1/20 0.55
HDAC6 Q9UBN7 1/20 0.55
ADORA3 P0DMS8 2/20 0.52
FGFR3 P22607 1/20 0.52
MAPK1 P28482 2/20 0.51
BCHE P06276 1/20 0.49
ADORA1 P30542 1/20 0.48
MEN1 O00255 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31503559 1.00 SMN1; SMN2 (0.67) SMN1; SMN2NPC1RAB9ATLR9KDR
SCHEMBL21777625 0.97 NPC1 (0.68) SMN1; SMN2NPC1RAB9ATLR9KDR
SCHEMBL28760253 0.93 NPC1 (0.67) SMN1; SMN2NPC1RAB9ATLR9KDR
SCHEMBL15850502 0.91 NPC1 (0.68) SMN1; SMN2NPC1RAB9ATLR9KDR
SCHEMBL30107670 0.91 NPC1 (0.68) SMN1; SMN2NPC1RAB9ATLR9KDR
SCHEMBL30665751 0.83 BCHE (0.63) SMN1; SMN2NPC1RAB9ATLR9KDR
SCHEMBL27323740 0.83 BCHE (0.63) SMN1; SMN2NPC1RAB9ATLR9KDR
SCHEMBL21793869 0.82 NPC1 (0.57) SMN1; SMN2NPC1RAB9ATLR9KDR
SCHEMBL30723191 0.82 NPC1 (0.57) SMN1; SMN2NPC1RAB9ATLR9KDR
SCHEMBL22661774 0.82 TLR9 (0.70) SMN1; SMN2NPC1RAB9ATLR9KDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025084253-A1 CARBAZOLE COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT 保土谷化学工業株式会社 2025-04-24 WO disclosed
CN-116997595-A Block copolymer and method for producing same, polyelectrolyte material, polyelectrolyte molded body, polyelectrolyte membrane, electrolyte membrane with catalyst layer, membrane electrode assembly, solid polymer fuel cell, and water-splitting hydrogen generator 东丽株式会社 2023-11-03 CN disclosed
CN-108043442-B Carbon-supported ruthenium nano material, preparation method thereof and application of carbon-supported ruthenium nano material in catalyzing reaction of alcohol and aromatic diamine 苏州大学 2021-03-19 CN disclosed