Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 5/20 | 0.36 |
| ▸ | CA1 | P00915 | 5/20 | 0.36 |
| ▸ | CA2 | P00918 | 5/20 | 0.36 |
| ▸ | CA5A | P35218 | 5/20 | 0.36 |
| ▸ | CA9 | Q16790 | 5/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | BRD2 | P25440 | 1/20 | 0.34 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.34 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.34 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2180653 | 0.85 | GPBAR1 (0.36) | — | |
| SCHEMBL1841780 | 0.81 | GRM1 (0.41) | GRM1KDM4ESMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL1842244 | 0.78 | DYRK1A (0.41) | KDM4ESMN1; SMN2ALDH1A1HSD17B10HPGD | |
| SCHEMBL2179449 | 0.76 | MAPT (0.39) | GRM1KDM4ESMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL1283081 | 0.76 | PIK3CD (0.41) | KDM4EALDH1A1HSD17B10RAB9ANPC1 | |
| SCHEMBL1707976 | 0.75 | ADORA2A (0.51) | GRM1KDM4ESMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL1841858 | 0.75 | IKBKB (0.36) | KDM4ESMN1; SMN2ALDH1A1HPGDCA12 | |
| SCHEMBL1708351 | 0.75 | NPC1 (0.47) | SMN1; SMN2ALDH1A1RAB9ANPC1HTT | |
| SCHEMBL1841862 | 0.72 | HTT (0.36) | GRM1KDM4ESMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL1841861 | 0.71 | SQOR (0.32) | KDM4EALDH1A1HPGDRAB9AIKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110166088-A1 | BENZOTHIAZOLES AND AZA-ANALOGUES THEREOF USE AS ANTIBACTERIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110166088-A1 | BENZOTHIAZOLES AND AZA-ANALOGUES THEREOF USE AS ANTIBACTERIAL AGENTS | TOP2B, TOP1, POLI | GRM1 2966/4885KDM4E 315/4885SMN1; SMN2 4463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.