SCHEMBL21794993

SCHEMBL21794993

c1ccc(-c2nc(-c3cccc4c3oc3ccc(-c5cccc6c5sc5ccccc56)cc34)nc(-c3cccc4c5ccccc5n(-c5ccccc5)c34)n2)cc1

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.38
PRKDC P78527 5/20 0.36
PIK3CD O00329 2/20 0.34
PIK3CB P42338 2/20 0.34
BRD4 O60885 1/20 0.33
PIK3CA P42336 1/20 0.33
MTOR P42345 1/20 0.33
PIK3CG P48736 1/20 0.33
KCNH2 Q12809 1/20 0.33
BRDT Q58F21 1/20 0.33
PTPRF P10586 2/20 0.30
PTPN2 P17706 2/20 0.30
PTPN1 P18031 2/20 0.30
SIRT2 Q8IXJ6 1/20 0.30
SIRT1 Q96EB6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23947787 0.93 PRKDC (0.36) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL24264009 0.92 PRKDC (0.42) ALOX5PRKDCPIK3CDPIK3CBSIRT2
SCHEMBL24216124 0.91 ALOX5 (0.40) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL24230966 0.91 PRKDC (0.35) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL22258040 0.90 PRKDC (0.33) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL23947910 0.90 ALOX5 (0.36) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL20754177 0.88 ALOX5 (0.38) ALOX5PRKDCPTPRFPTPN2PTPN1
SCHEMBL24216524 0.88 ALOX5 (0.47) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL23947318 0.88 PRKDC (0.40) ALOX5PRKDCPIK3CDPIK3CBSIRT2
SCHEMBL20922227 0.88 PRKDC (0.33) ALOX5PRKDCPIK3CDPIK3CBBRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220123224-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2022-04-21 US disclosed
WO-2020045831-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING SAME 덕산네오룩스 주식회사 2020-03-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220123224-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF PIEZO1, OR51E2, OR10J3 ALOX5 849/4885PRKDC 3860/4885PIK3CD 3212/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.