Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 9/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15420103 | 0.82 | GRM5 (0.39) | GRM5MAPK1XDHGRM4FFAR4 | |
| SCHEMBL21795663 | 0.77 | XDH (0.39) | GRM5XDHGRM4FFAR4FPR2 | |
| SCHEMBL15420514 | 0.77 | GRM5 (0.36) | GRM5XDHGRM4FFAR4FFAR1 | |
| SCHEMBL12987104 | 0.76 | GRM5 (0.36) | GRM5XDHGRM4FFAR4FFAR1 | |
| SCHEMBL15420273 | 0.75 | GRM5 (0.36) | GRM5XDHGRM4FFAR4FFAR1 | |
| SCHEMBL12987565 | 0.75 | GRM5 (0.36) | GRM5XDHGRM4FFAR4FFAR1 | |
| SCHEMBL12987181 | 0.75 | GRM5 (0.36) | GRM5XDHGRM4FFAR4FFAR1 | |
| SCHEMBL13192630 | 0.75 | GRM5 (0.36) | GRM5XDHGRM4FFAR4FFAR1 | |
| SCHEMBL12987659 | 0.74 | GRM5 (0.36) | GRM5XDHGRM4FFAR4FFAR1 | |
| SCHEMBL12987780 | 0.74 | GRM5 (0.36) | GRM5XDHGRM4FFAR4FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2694472-B1 | SULFONAMIDE DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICALS CO (JP) | 2020-03-11 | — | — | EP | disclosed |