Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 3/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 2/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | MERTK | Q12866 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21795648 | 0.88 | XDH (0.39) | XDHGPR119GRM4FFAR4DGAT1 | |
| SCHEMBL21795636 | 0.88 | XDH (0.39) | XDHGPR119GRM4FFAR4DGAT1 | |
| SCHEMBL21795638 | 0.87 | KDM4E (0.42) | XDHGPR119SCN9A | |
| SCHEMBL12986558 | 0.87 | GRM5 (0.38) | GRM5SCN9AGRM4FFAR4AXL | |
| SCHEMBL15420322 | 0.80 | GRM5 (0.41) | XDHGRM5HDAC1HDAC2GRIA2 | |
| SCHEMBL21795659 | 0.80 | NPC1 (0.39) | XDHGPR119NPC1FFAR4 | |
| SCHEMBL21795667 | 0.78 | FFAR4 (0.37) | GRM4FFAR4DGAT1 | |
| SCHEMBL21795670 | 0.78 | KCNH2 (0.35) | GPR119GRM4FFAR4DGAT1 | |
| SCHEMBL21795654 | 0.77 | GRM5 (0.37) | XDHGRM5FPR2SCN9AGRM4 | |
| SCHEMBL21795640 | 0.77 | PARP15 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2694472-B1 | SULFONAMIDE DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICALS CO (JP) | 2020-03-11 | — | — | EP | disclosed |