Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | AHR | P35869 | 1/20 | 0.69 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | HTR2A | P28223 | 4/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.60 |
| ▸ | HTR2C | P28335 | 3/20 | 0.60 |
| ▸ | HTR6 | P50406 | 3/20 | 0.60 |
| ▸ | HTR1D | P28221 | 2/20 | 0.60 |
| ▸ | HTR1B | P28222 | 2/20 | 0.60 |
| ▸ | HTR7 | P34969 | 2/20 | 0.60 |
| ▸ | MPO | P05164 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | CTSK | P43235 | 1/20 | 0.60 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28214148 | 0.84 | MEN1 (0.55) | MEN1KMT2ACYP3A4MAPTAHR | |
| SCHEMBL3676456 | 0.84 | SLC6A4 (0.63) | MEN1KMT2ACYP3A4MAPTAHR | |
| SCHEMBL316624 | 0.83 | HTR2A (0.67) | MEN1KMT2ACYP3A4MAPTAHR | |
| SCHEMBL7495793 | 0.83 | SLC6A4 (0.61) | MEN1KMT2ACYP3A4MAPTAHR | |
| SCHEMBL7004146 | 0.83 | HTR2A (0.71) | MEN1KMT2ACYP3A4MAPTAHR | |
| SCHEMBL7005718 | 0.83 | HTR2A (0.71) | MEN1KMT2ACYP3A4MAPTAHR | |
| Arundine SCHEMBL325162 | 0.82 | MEN1 (1.00) | MEN1KMT2ACYP3A4MAPTAHR | |
| SCHEMBL4985934 | 0.82 | HTR2A (0.77) | MEN1KMT2ACYP3A4MAPTAHR | |
| SCHEMBL7496450 | 0.81 | SLC6A4 (0.59) | MEN1KMT2ACYP3A4MAPTAHR | |
| SCHEMBL7004071 | 0.81 | HTR2A (0.69) | MEN1KMT2ACYP3A4MAPTAHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2469 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112624955-B | Separation method of 3-indoloethyl (3 '-methyl-2' -ketone) valeramide | 西北农林科技大学 | 2024-07-09 | — | — | CN | claimed |
| US-20240207253-A1 | Inhibitors of CDR1 for Reversal of Azole Drug Resistance in Fungal Infections | THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS | 2024-06-27 | — | — | US | claimed |
| CN-117448254-A | Preparation method and application of Glycyrrhiza glabra stem cells | 广州梵之容化妆品有限公司 | 2024-01-26 | — | — | CN | claimed |
| WO-2023217764-A1 | NOX INHIBITORS FOR USE IN THE TREATMENT OF ALPORT SYNDROME | CALLIDITAS THERAPEUTICS SUISSE SA (CH) | 2023-11-16 | — | — | WO | claimed |
| US-20230242572-A1 | a-CARBONYL ALKENYL ESTER PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | JIANGXI NORMAL UNIVERSITY (CN) | 2023-08-03 | — | — | US | claimed |
| CN-113292430-B | Alpha-carbonyl alkenyl ester compound and preparation method and application thereof | 江西师范大学 | 2022-11-29 | — | — | CN | claimed |
| CN-112778067-B | Method for synthesizing thioamide compound by catalyzing 1,2, 3-thiadiazole compound and amine with copper | 华南理工大学 | 2022-05-24 | — | — | CN | claimed |
| CN-113717141-A | Formononetin derivative and preparation method and application thereof | 云南大学 | 2021-11-30 | — | — | CN | claimed |
| CN-113712970-A | Application of formononetin derivative in preparation of medicine for treating or preventing perimenopausal syndrome | 云南大学 | 2021-11-30 | — | — | CN | claimed |
| EP-3523316-B1 | MELANOCORTIN-1-RECEPTOR AGONISTS | DSM IP ASSETS BV (NL) | 2021-11-03 | — | — | EP | claimed |
| US-4528293-A | Heteroaromatic derivatives of iminomethyl piperidines and use to inhibit gastric acid secretion | MCNEILAB, INC. (US) | 1985-07-09 | — | — | US | claimed |
| US-4512979-A | Dipeptides containing thialysine and related amino acids as antihypertensives | MERCK & CO., INC. (US) | 1985-04-23 | — | — | US | claimed |
| EP-0132964-A2 | 2-Azabicyclo[2.2.2]octane derivatives | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1985-02-13 | — | — | EP | claimed |
| US-4496542-A | HYPOTENSIVE AGENTS; ENZYME INHIBITORS | USV PHARMACEUTICAL CORPORATION (US) | 1985-01-29 | — | — | US | claimed |
| EP-0061768-A1 | N-amido substituted dipeptides | USV PHARMACEUTICAL CORPORATION (US) | 1982-10-06 | — | — | EP | claimed |
| EP-0061186-A1 | Dipeptides containing thialysine and homologs as antihypertensives | MERCK & CO. INC. (US) | 1982-09-29 | — | — | EP | claimed |
| EP-0004952-B1 | SPIRO-(DIHYDROBENZOFURANPIPERIDINES AND -PYRROLIDINES) AND DERIVATIVES THEREOF, METHODS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-04-07 | — | — | EP | claimed |
| US-4188389-A | 1,2,3,4-Tetrahydropyrrolo(1,2-A)pyrazines | AYERST MCKENNA & HARRISON, INC. (CA) | 1980-02-12 | — | — | US | claimed |
| EP-0004952-A1 | Spiro-(dihydrobenzofuranpiperidines and -pyrrolidines) and derivatives thereof, methods for their preparation and medicines containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-10-31 | — | — | EP | claimed |
| US-4093628-A | HYPOTENSIVE AGENTS, BLOCKING AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1978-06-06 | — | — | US | claimed |