Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 19/20 | 0.83 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.72 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.72 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.72 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.72 |
| ▸ | EGFR | P00533 | 2/20 | 0.72 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.72 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.72 |
| ▸ | BRD4 | O60885 | 2/20 | 0.61 |
| ▸ | BRDT | Q58F21 | 2/20 | 0.61 |
| ▸ | BRD2 | P25440 | 1/20 | 0.61 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.61 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.58 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.58 |
| ▸ | LCK | P06239 | 2/20 | 0.58 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.58 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.58 |
| ▸ | MINK1 | Q8N4C8 | 2/20 | 0.58 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.58 |
| ▸ | MAP4K5 | Q9Y4K4 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24170876 | 0.91 | MAPK14 (1.00) | MAPK14MAPK13CSNK1DMAPK12MAPK11 | |
| SCHEMBL24170595 | 0.91 | MAPK14 (0.81) | MAPK14MAPK13CSNK1DMAPK12MAPK11 | |
| SCHEMBL1640306 | 0.90 | MAPK14 (1.00) | MAPK14MAPK13CSNK1DMAPK12MAPK11 | |
| SCHEMBL24170875 | 0.90 | MAPK14 (0.80) | MAPK14MAPK13CSNK1DMAPK12MAPK11 | |
| SCHEMBL27441160 | 0.90 | MAPK14 (1.00) | MAPK14MAPK13CSNK1DMAPK12MAPK11 | |
| SCHEMBL24170872 | 0.89 | MAPK14 (0.78) | MAPK14MAPK13CSNK1DMAPK12MAPK11 | |
| SCHEMBL29841901 | 0.89 | MAPK14 (0.82) | MAPK14MAPK13CSNK1DMAPK12MAPK11 | |
| SCHEMBL28623475 | 0.89 | MAPK14 (0.82) | MAPK14MAPK13CSNK1DMAPK12MAPK11 | |
| SCHEMBL29841951 | 0.88 | MAPK14 (0.70) | MAPK14MAPK13CSNK1DMAPK12MAPK11 | |
| SCHEMBL29841960 | 0.88 | MAPK14 (0.70) | MAPK14MAPK13CSNK1DMAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3619204-B1 | COMPOUNDS FOR THE TREATMENT OF RESPIRATORY DISEASES | TIANLI BIOTECH PTY LTD (AU) | 2025-10-01 | — | — | EP | disclosed |
| US-20220380343-A1 | COMPOUNDS FOR THE TREATMENT OF RESPIRATORY DISEASES | TIANLI BIOTECH PTY LTD (AU) | 2022-12-01 | — | — | US | disclosed |
| US-20200079757-A1 | COMPOUNDS FOR THE TREATMENT OF RESPIRATORY DISEASES | THE UNIVERSITY OF MELBOURNE (AU) | 2020-03-12 | — | — | US | disclosed |
| CN-110753688-A | Compounds for the treatment of respiratory diseases | 墨尔本大学 | 2020-02-04 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220380343-A1 | COMPOUNDS FOR THE TREATMENT OF RESPIRATORY DISEASES | LTC4S, LTB4R2, LTB4R | MAPK14 4326/4885MAPK13 3615/4885CSNK1D 4223/4885 |
| US-20200079757-A1 | COMPOUNDS FOR THE TREATMENT OF RESPIRATORY DISEASES | LTC4S, LTB4R2, LTB4R | MAPK14 4326/4885MAPK13 3615/4885CSNK1D 4223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.