SCHEMBL21797185

SCHEMBL21797185

CCCNc1nccc(C(OC)OC)n1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.43
RAB9A P51151 1/20 0.43
ACACB O00763 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.39
HRH4 Q9H3N8 3/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
CYP1A2 P05177 1/20 0.38
CYP2C19 P33261 1/20 0.38
DNM2 P50570 2/20 0.38
CDC7 O00311 1/20 0.38
MAPK8 P45983 1/20 0.36
MAPT P10636 2/20 0.36
MERTK Q12866 1/20 0.36
HTR7 P34969 2/20 0.35
MKNK1 Q9BUB5 1/20 0.34
MKNK2 Q9HBH9 1/20 0.34
MAPK9 P45984 1/20 0.34
MAPK10 P53779 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16815715 0.86 MKNK1 (0.47) KMT2ARAB9AL3MBTL1SMN1; SMN2CYP1A2
SCHEMBL84398 0.82 ACACB (0.42) ACACBHRH4DNM2CDC7MAPK8
SCHEMBL21797166 0.79 CDC7 (0.46) KMT2ARAB9AL3MBTL1CYP1A2CYP2C19
SCHEMBL1800915 0.78 SMN1; SMN2 (0.43) KMT2ARAB9AL3MBTL1SMN1; SMN2MAPT
SCHEMBL12411162 0.76 MAPK8 (0.47) KMT2ARAB9AACACBL3MBTL1HRH4
SCHEMBL14516259 0.76 CYP1A2 (0.45) HRH4CYP1A2CYP2C19DNM2CDC7
SCHEMBL28605998 0.74 IDH1 (0.42) ACACBHRH4DNM2CDC7MAPK8
SCHEMBL13384588 0.73 HRH4 (0.52) HRH4DNM2MAPK8MERTKHTR7
SCHEMBL91452 0.73 NPSR1 (0.46) RAB9AHRH4SMN1; SMN2DNM2CDC7
SCHEMBL16815728 0.72 KMT2A (0.46) KMT2ARAB9AL3MBTL1SMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3619204-B1 COMPOUNDS FOR THE TREATMENT OF RESPIRATORY DISEASES TIANLI BIOTECH PTY LTD (AU) 2025-10-01 EP disclosed
US-20220380343-A1 COMPOUNDS FOR THE TREATMENT OF RESPIRATORY DISEASES TIANLI BIOTECH PTY LTD (AU) 2022-12-01 US disclosed
US-20200079757-A1 COMPOUNDS FOR THE TREATMENT OF RESPIRATORY DISEASES THE UNIVERSITY OF MELBOURNE (AU) 2020-03-12 US disclosed
CN-110753688-A Compounds for the treatment of respiratory diseases 墨尔本大学 2020-02-04 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220380343-A1 COMPOUNDS FOR THE TREATMENT OF RESPIRATORY DISEASES LTC4S, LTB4R2, LTB4R KMT2A 3310/4885RAB9A 2285/4885ACACB 245/4885
US-20200079757-A1 COMPOUNDS FOR THE TREATMENT OF RESPIRATORY DISEASES LTC4S, LTB4R2, LTB4R KMT2A 3310/4885RAB9A 2285/4885ACACB 245/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.