Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 2/20 | 0.34 |
| ▸ | RPTOR | Q8N122 | 2/20 | 0.34 |
| ▸ | MLST8 | Q9BVC4 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | IL1B | P01584 | 1/20 | 0.33 |
| ▸ | FER | P16591 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | HIPK1 | Q86Z02 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2179806 | 1.00 | MTOR (0.34) | MTORRPTORMLST8ALDH1A1KDM4E | |
| SCHEMBL1935533 | 0.92 | IRAK4 (0.33) | ALDH1A1KDM4EHSD17B10MAPTCSNK2A1 | |
| SCHEMBL1935537 | 0.92 | IRAK4 (0.33) | ALDH1A1KDM4EHSD17B10MAPTCSNK2A1 | |
| SCHEMBL1936072 | 0.90 | ROCK2 (0.39) | ALDH1A1KDM4EHSD17B10MAPTCSNK2A1 | |
| SCHEMBL1936073 | 0.90 | ROCK2 (0.39) | ALDH1A1KDM4EHSD17B10MAPTCSNK2A1 | |
| SCHEMBL2180970 | 0.90 | KDM4E (0.35) | ALDH1A1KDM4EHSD17B10MAPTCSNK2A1 | |
| SCHEMBL2179225 | 0.90 | IRAK4 (0.33) | ALDH1A1KDM4EHSD17B10MAPTCSNK2A1 | |
| SCHEMBL2179229 | 0.90 | IRAK4 (0.33) | ALDH1A1KDM4EHSD17B10MAPTCSNK2A1 | |
| SCHEMBL2180968 | 0.90 | KDM4E (0.35) | ALDH1A1KDM4EHSD17B10MAPTCSNK2A1 | |
| SCHEMBL1936931 | 0.84 | ROCK2 (0.42) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110166161-A1 | HETEROCYCLIC CARBOXAMIDE COMPOUNDS | ASTELLAS PHARMA INC. (JP) | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110166161-A1 | HETEROCYCLIC CARBOXAMIDE COMPOUNDS | ROCK1, ROCK2, RHOT2 | MTOR 125/4885RPTOR 502/4885MLST8 1747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.