Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.72 |
| ▸ | LMNA | P02545 | 4/20 | 0.72 |
| ▸ | MAPT | P10636 | 4/20 | 0.72 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.72 |
| ▸ | MEN1 | O00255 | 2/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | RECQL | P46063 | 1/20 | 0.72 |
| ▸ | HPGD | P15428 | 4/20 | 0.63 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.63 |
| ▸ | THRB | P10828 | 3/20 | 0.60 |
| ▸ | DHODH | Q02127 | 3/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | TOP1 | P11387 | 2/20 | 0.55 |
| ▸ | AURKA | O14965 | 1/20 | 0.51 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27899449 | 0.91 | ALDH1A1 (0.80) | ALDH1A1KDM4ELMNAMAPTNPSR1 | |
| SCHEMBL28318020 | 0.91 | ALDH1A1 (0.80) | ALDH1A1KDM4ELMNAMAPTNPSR1 | |
| SCHEMBL18698068 | 0.91 | ALDH1A1 (0.85) | ALDH1A1KDM4ELMNAMAPTNPSR1 | |
| SCHEMBL12453674 | 0.86 | TOP1 (0.61) | ALDH1A1KDM4ELMNAMAPTNPSR1 | |
| SCHEMBL28175731 | 0.86 | ALDH1A1 (0.71) | ALDH1A1KDM4ELMNAMAPTNPSR1 | |
| SCHEMBL27991439 | 0.85 | ALDH1A1 (0.72) | ALDH1A1KDM4ELMNAMAPTNPSR1 | |
| SCHEMBL13931511 | 0.84 | ALDH1A1 (0.70) | ALDH1A1KDM4ELMNAMAPTNPSR1 | |
| SCHEMBL28349800 | 0.84 | DHODH (0.61) | ALDH1A1KDM4ELMNAMAPTNPSR1 | |
| SCHEMBL21799200 | 0.83 | ACACA (0.74) | ALDH1A1KDM4ELMNAMAPTNPSR1 | |
| SCHEMBL27986490 | 0.83 | ACACA (0.74) | ALDH1A1KDM4ELMNAMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10730838-B2 | Green preparation method for quinoline compounds | DALIAN UNIVERSITY OF TECHNOLOGY (CN) | 2020-08-04 | — | — | US | disclosed |
| US-10730838-B2 | Green preparation method for quinoline compounds | DALIAN UNIVERSITY OF TECHNOLOGY (CN) | 2020-08-04 | — | — | US | disclosed |
| US-20200079737-A1 | GREEN PREPARATION METHOD FOR QUINOLINE COMPOUNDS | DALIAN UNIVERSITY OF TECHNOLOGY (CN) | 2020-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200079737-A1 | GREEN PREPARATION METHOD FOR QUINOLINE COMPOUNDS | NQO1, TYR, ABCG2 | ALDH1A1 558/4885KDM4E 3307/4885LMNA 1360/4885 |
| US-10730838-B2 | Green preparation method for quinoline compounds | NQO1, TYR, ABCG2 | ALDH1A1 558/4885KDM4E 3307/4885LMNA 1360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.