SCHEMBL21799264

SCHEMBL21799264

NCCCS(=O)(=O)OCCO

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.44
LMNA P02545 2/20 0.38
GMNN O75496 1/20 0.38
ALDH1A1 P00352 1/20 0.38
TP53 P04637 1/20 0.38
TSHR P16473 1/20 0.38
MAPK1 P28482 1/20 0.38
THPO P40225 1/20 0.38
HBB P68871 1/20 0.38
PMP22 Q01453 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
SLC6A6 P31641 1/20 0.32
CYP2C19 P33261 1/20 0.32
BLM P54132 1/20 0.32
CA1 P00915 7/20 0.31
CA2 P00918 7/20 0.31
CA9 Q16790 7/20 0.31
CA12 O43570 2/20 0.30
CA3 P07451 2/20 0.30
CA4 P22748 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5328947 0.86 LMNA (0.40) APPLMNAALDH1A1TSHRSLC6A6
SCHEMBL29172886 0.85 APP (0.38) APPLMNAGMNNALDH1A1TP53
SCHEMBL28507033 0.84 LMNA (0.39) APPLMNAALDH1A1TSHRSLC6A6
SCHEMBL28593624 0.84 APP (0.44) APPLMNAGMNNALDH1A1TP53
SCHEMBL27583722 0.83 APP (0.37) APPLMNAGMNNALDH1A1TP53
SCHEMBL27583866 0.82 CA2 (0.35) APPCA1CA2CA9CA12
Choline SCHEMBL2304925 0.79 LMNA (0.38) APPLMNATSHRSMN1; SMN2CYP2C19
SCHEMBL8608172 0.79 TSHR (0.33) TSHRMAPK1CA1CA2CA9
SCHEMBL27965502 0.78 TSHR (0.43) LMNAALDH1A1TP53TSHRMAPK1
SCHEMBL7098756 0.77 LMNA (0.35) APPLMNAALDH1A1TSHRSLC6A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110669188-B Waterborne polyurethane coating capable of self-repairing through ultraviolet light and preparation method thereof 南京林业大学 2020-10-13 CN claimed
CN-110669188-A Waterborne polyurethane coating capable of self-repairing through ultraviolet light and preparation method thereof 南京林业大学 2020-01-10 CN claimed
CN-117481116-A Self-dispersing polyurethane pesticide slow-release microcapsule suspending agent and preparation method thereof 上海师范大学 2024-02-02 CN disclosed
US-20230211014-A1 AAV Gene Therapy for Spastic Paraplegia Genetic Cures for Kids Inc. (AU) 2023-07-06 US disclosed
CN-115820145-A Adhesive tape with cross-linked polyurethane carrier 德莎欧洲股份公司 2023-03-21 CN disclosed
CN-114075410-B Adhesive tape with polyurethane carrier 德莎欧洲股份公司 2023-03-14 CN disclosed
CN-114075409-B Adhesive tape with polyurethane carrier 德莎欧洲股份公司 2022-08-30 CN disclosed
CN-114075410-A Adhesive tape with polyurethane carrier 德莎欧洲股份公司 2022-02-22 CN disclosed
CN-114075409-A Adhesive tape with polyurethane carrier 德莎欧洲股份公司 2022-02-22 CN disclosed
CN-110669188-B Waterborne polyurethane coating capable of self-repairing through ultraviolet light and preparation method thereof 南京林业大学 2020-10-13 CN disclosed
CN-110903453-A Polyurethane foam, adhesive tape, use thereof, and method for producing polyurethane foam 德莎欧洲股份公司 2020-03-24 CN disclosed
CN-101759842-B Flame-retardant aqueous polyurethane dispersion IND TECH RES INST 2012-11-28 CN disclosed
CN-102020774-B method for forming aqueous polyurethane IND TECH RES INST 2012-07-18 CN disclosed
CN-102020774-A Method for forming aqueous polyurethane IND TECH RES INST 2011-04-20 CN disclosed
CN-101759842-A Flame-retardant aqueous polyurethane dispersion IND TECH RES INST 2010-06-30 CN disclosed
CN-1281811-C Synthetic leather structure containing water-based aromatic polyurethane film layer INST IND TECHNOLOGY (CN) 2006-10-25 CN disclosed
CN-1226323-C High-performance waterborne polyurethane and preparation method thereof IND TECH RES INST (CN) 2005-11-09 CN disclosed
CN-1657688-A Synthetic leather structure containing water-based aromatic polyurethane film layer INST IND TECHNOLOGY (CN) 2005-08-24 CN disclosed
CN-1629244-A Adhesive comprising aromatic aqueous polyurethane dispersion and flocking method using the same IND TECH RES INST (CN) 2005-06-22 CN disclosed
CN-1405196-A High-performance waterborne polyurethane and preparation method thereof IND TECH RES INST (CN) 2003-03-26 CN disclosed