Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1447880 | 0.86 | THRB (0.52) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL27642349 | 0.82 | TSHR (0.55) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL27733083 | 0.82 | TSHR (0.55) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL15090837 | 0.82 | THRB (0.52) | THRBTSHRPOLBAPEX1HTT | |
| Methacrylic Acid SCHEMBL11580464 | 0.81 | THRB (0.47) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL28029508 | 0.80 | THRB (0.50) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL41669 | 0.79 | TSHR (0.63) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL496658 | 0.79 | TSHR (0.57) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL665302 | 0.79 | THRB (0.53) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL11023086 | 0.78 | THRB (0.48) | THRBTSHRPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2492289-B1 | POLYMERIZABLE COMPOSITION AND DENTAL MATERIAL | KURARAY NORITAKE DENTAL INC (JP) | 2020-03-18 | — | — | EP | claimed |