SCHEMBL21799341

SCHEMBL21799341

CCOC(=O)C1(C)C=CC=CC1N

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.33
ALDH1A1 P00352 2/20 0.31
LMNA P02545 1/20 0.30
HSD17B10 Q99714 1/20 0.30
BRD4 O60885 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29234772 0.80 LMNA (0.34) ALDH1A1LMNA
SCHEMBL1004396 0.76 BRD4 (0.31) ALOX15ALDH1A1LMNABRD4
SCHEMBL11575353 0.74
SCHEMBL16774611 0.74
SCHEMBL11841327 0.71 ALOX15 (0.32) ALOX15ALDH1A1
SCHEMBL11813011 0.71
SCHEMBL8542162 0.70
SCHEMBL8824808 0.70
SCHEMBL28625080 0.68 ATM (0.30) ALDH1A1
SCHEMBL816511 0.67 LMNA (0.35) ALDH1A1LMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3621952-A1 METHOD FOR THE PRODUCTION OF PHENYLGUANIDINES OR THE SALTS THEREOF AlzChem Trostberg GmbH (DE) 2020-03-18 EP disclosed