SCHEMBL21799424

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21799396	0.91	SGMS2 (0.49)	SGMS2CYP11B1CYP11B2CYP19A1LRRK2
	SCHEMBL21799397	0.85	NPC1 (0.54)	SGMS2CYP11B1CYP11B2LRRK2KMT2A
	SCHEMBL21799410	0.80	IRAK4 (0.43)	IRAK4ALDH1A1
	SCHEMBL21799433	0.80	IRAK4 (0.46)	IRAK4KMT2A
	SCHEMBL24726394	0.77	JAK2 (0.41)	SGMS2IRAK4LRRK2KMT2A
	SCHEMBL12800042	0.75	IRAK4 (0.50)	IRAK4KMT2AALDH1A1HPGD
	SCHEMBL21799422	0.75	IRAK4 (0.50)	IRAK4KMT2AALDH1A1
	SCHEMBL22982440	0.73	IRAK4 (0.44)	IRAK4KMT2ALMNATDP1ALDH1A1
	SCHEMBL29413977	0.73	IRAK4 (0.44)	IRAK4KMT2ALMNATDP1ALDH1A1
	SCHEMBL168289	0.73	DGAT1 (0.45)	CYP11B1CYP11B2CYP19A1IRAK4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.