SCHEMBL21799529

SCHEMBL21799529

NCc1cccc(CC2CCNCC2)c1

nearest known ligand 0.62

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 1/20 0.62
SLC6A4 P31645 3/20 0.43
EED O75530 1/20 0.41
PRMT6 Q96LA8 1/20 0.41
PNMT P11086 1/20 0.40
ENPP2 Q13822 1/20 0.40
EP300 Q09472 1/20 0.40
IKBKB O14920 1/20 0.39
CHUK O15111 1/20 0.39
LOXL2 Q9Y4K0 1/20 0.39
ACP1 P24666 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13761198 0.92 GBA1 (0.57) GBA1SLC6A4EEDEP300IKBKB
SCHEMBL21799757 0.85 GBA1 (0.66) GBA1SLC6A4PRMT6EP300LOXL2
SCHEMBL22170191 0.84 PRMT6 (0.49) GBA1EEDPRMT6PNMTENPP2
SCHEMBL1867326 0.83 GBA1 (0.62) GBA1SLC6A4EEDACP1
SCHEMBL18617326 0.83 GBA1 (0.62) GBA1SLC6A4EEDACP1
SCHEMBL27785492 0.79 GBA1 (0.62) GBA1SLC6A4ENPP2
SCHEMBL3166228 0.79 GBA1 (0.62) GBA1SLC6A4PNMTACP1
SCHEMBL3958847 0.79 GBA1 (0.62) GBA1SLC6A4EED
SCHEMBL3966432 0.79 GBA1 (0.62) GBA1SLC6A4
SCHEMBL25133414 0.79 GBA1 (0.57) GBA1SLC6A4EEDACP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3623398-B1 RESIN COMPOSITION COMPRISING A MODIFIED BLOCK COPOLYMER AND METHOD FOR PRODUCING MODIFIED BLOCK COPOLYMER ASAHI CHEMICAL IND (JP) 2024-08-28 EP disclosed
CN-110603273-B Modified block copolymer, method for producing modified block copolymer, and resin composition 旭化成株式会社 2022-10-14 CN disclosed
US-11124593-B2 Modified block copolymer, method for producing modified block copolymer, and resin composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2021-09-21 US disclosed
US-20200199282-A1 Modified Block Copolymer, Method for Producing Modified Block Copolymer, and Resin Composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2020-06-25 US disclosed
EP-3623398-A1 MODIFIED BLOCK COPOLYMER, METHOD FOR PRODUCING MODIFIED BLOCK COPOLYMER, AND RESIN COMPOSITION Asahi Kasei Kabushiki Kaisha (JP) 2020-03-18 EP disclosed