SCHEMBL21799757

SCHEMBL21799757

NCc1ccc(CC2CCNCC2)cc1

nearest known ligand 0.67

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 1/20 0.66
EP300 Q09472 1/20 0.47
SLC6A4 P31645 3/20 0.43
HRH3 Q9Y5N1 3/20 0.41
HRH4 Q9H3N8 1/20 0.41
PRMT3 O60678 1/20 0.39
CARM1 Q86X55 1/20 0.39
PRMT6 Q96LA8 1/20 0.39
PRMT1 Q99873 1/20 0.39
PRMT8 Q9NR22 1/20 0.39
PRMT5 O14744 1/20 0.38
WDR77 Q9BQA1 1/20 0.38
LOXL2 Q9Y4K0 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21799529 0.85 GBA1 (0.62) GBA1EP300SLC6A4PRMT6LOXL2
SCHEMBL1264017 0.84 GBA1 (0.66) GBA1EP300SLC6A4HRH3HRH4
SCHEMBL13761198 0.81 GBA1 (0.57) GBA1EP300SLC6A4
SCHEMBL4245166 0.80 GBA1 (0.66) GBA1EP300SLC6A4HRH3HRH4
SCHEMBL2948678 0.80 GBA1 (0.66) GBA1SLC6A4PRMT5WDR77
SCHEMBL25133603 0.80 GBA1 (0.66) GBA1EP300SLC6A4HRH3HRH4
SCHEMBL895063 0.80 GBA1 (0.66) GBA1SLC6A4
SCHEMBL578602 0.80 GBA1 (0.66) GBA1EP300SLC6A4HRH3HRH4
SCHEMBL15718702 0.80 GBA1 (0.66) GBA1EP300SLC6A4HRH3HRH4
SCHEMBL894700 0.80 GBA1 (0.66) GBA1SLC6A4HRH3HRH4PRMT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3623398-B1 RESIN COMPOSITION COMPRISING A MODIFIED BLOCK COPOLYMER AND METHOD FOR PRODUCING MODIFIED BLOCK COPOLYMER ASAHI CHEMICAL IND (JP) 2024-08-28 EP disclosed
US-11124593-B2 Modified block copolymer, method for producing modified block copolymer, and resin composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2021-09-21 US disclosed
US-20200199282-A1 Modified Block Copolymer, Method for Producing Modified Block Copolymer, and Resin Composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2020-06-25 US disclosed
EP-3623398-A1 MODIFIED BLOCK COPOLYMER, METHOD FOR PRODUCING MODIFIED BLOCK COPOLYMER, AND RESIN COMPOSITION Asahi Kasei Kabushiki Kaisha (JP) 2020-03-18 EP disclosed