SCHEMBL21799663

SCHEMBL21799663

Nc1cccc(NC2CCCCC2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.50
GAA P10253 4/20 0.50
MAPT P10636 3/20 0.50
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
TDP1 Q9NUW8 2/20 0.47
LMNA P02545 2/20 0.47
GFER P55789 1/20 0.47
DDB1 Q16531 3/20 0.46
CRBN Q96SW2 3/20 0.46
DDX3X O00571 1/20 0.44
ALDH1A1 P00352 2/20 0.44
APAF1 O14727 1/20 0.44
MAPK1 P28482 1/20 0.44
BLM P54132 1/20 0.44
HSD17B10 Q99714 1/20 0.44
RAPGEF4 Q8WZA2 1/20 0.43
NPY5R Q15761 1/20 0.41
CYP3A4 P08684 2/20 0.41
CASP1 P29466 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29922322 1.00 KDM4E (0.50) KDM4EGAAMAPTMEN1KMT2A
SCHEMBL15928723 0.98 KDM4E (0.48) KDM4EGAAMAPTMEN1KMT2A
SCHEMBL24661857 0.94 KDM4E (0.48) KDM4EGAAMAPTMEN1KMT2A
SCHEMBL4533550 0.90 KDM4E (0.52) KDM4EGAAMAPTMEN1KMT2A
SCHEMBL3427795 0.88 KDM4E (0.49) KDM4EGAAMAPTMEN1KMT2A
SCHEMBL3768702 0.86 KDM4E (0.46) KDM4EGAAMAPTMEN1KMT2A
SCHEMBL19675712 0.83 DDB1 (0.43) KDM4EGAAMAPTMEN1KMT2A
SCHEMBL4069931 0.81 DDB1 (0.48) KDM4EGAAMAPTMEN1KMT2A
SCHEMBL31357223 0.80 PRKCZ (0.52) DDB1CRBNMAPK1
SCHEMBL19675966 0.80 PRKCZ (0.52) DDB1CRBNMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3623398-B1 RESIN COMPOSITION COMPRISING A MODIFIED BLOCK COPOLYMER AND METHOD FOR PRODUCING MODIFIED BLOCK COPOLYMER ASAHI CHEMICAL IND (JP) 2024-08-28 EP disclosed
CN-110603273-B Modified block copolymer, method for producing modified block copolymer, and resin composition 旭化成株式会社 2022-10-14 CN disclosed
US-11124593-B2 Modified block copolymer, method for producing modified block copolymer, and resin composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2021-09-21 US disclosed
WO-2021133689-A2 LIPOXYGENASE INHIBITORS SRI INTERNATIONAL (US) 2021-07-01 WO disclosed
US-20200199282-A1 Modified Block Copolymer, Method for Producing Modified Block Copolymer, and Resin Composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2020-06-25 US disclosed
EP-3623398-A1 MODIFIED BLOCK COPOLYMER, METHOD FOR PRODUCING MODIFIED BLOCK COPOLYMER, AND RESIN COMPOSITION Asahi Kasei Kabushiki Kaisha (JP) 2020-03-18 EP disclosed
CN-110603273-A Modified block copolymer, method for producing modified block copolymer, and resin composition 旭化成株式会社 2019-12-20 CN disclosed
CN-101896585-A Alkylated 1, 3-phenylenediamine compound and process for producing the same CHEMTURA CORP 2010-11-24 CN disclosed