SCHEMBL21799768

SCHEMBL21799768

CCCC(CC)Nc1cccc(N)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.42
KDM4E B2RXH2 1/20 0.42
MEN1 O00255 1/20 0.42
LMNA P02545 1/20 0.42
GAA P10253 1/20 0.42
GFER P55789 1/20 0.42
KMT2A Q03164 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
ALDH1A1 P00352 3/20 0.41
DDX3X O00571 2/20 0.40
RAPGEF4 Q8WZA2 1/20 0.39
MAPK1 P28482 1/20 0.37
CYP3A4 P08684 2/20 0.36
TP53 P04637 1/20 0.36
DYRK3 O43781 1/20 0.36
CCNT1 O60563 1/20 0.36
CCNA2 P20248 1/20 0.36
CDK2 P24941 1/20 0.36
CDK9 P50750 1/20 0.36
CDK5 Q00535 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29922424 1.00 MAPT (0.42) MAPTKDM4EMEN1LMNAGAA
SCHEMBL15928729 0.90 MAPT (0.47) MAPTKDM4EMEN1LMNAGAA
SCHEMBL21799838 0.81 GAA (0.43) MAPTKDM4EMEN1LMNAGAA
SCHEMBL29922665 0.81 GAA (0.43) MAPTKDM4EMEN1LMNAGAA
SCHEMBL21799960 0.79 ALDH1A1 (0.42) MAPTGAAGFERTDP1ALDH1A1
SCHEMBL10889654 0.78 TDP1 (0.46) MAPTMEN1LMNAKMT2ATDP1
SCHEMBL11765238 0.77 ALDH1A1 (0.55) MAPTKDM4EMEN1LMNAGAA
SCHEMBL19935775 0.76 TAS1R3 (0.53) MAPTMEN1LMNAGAAKMT2A
SCHEMBL21799891 0.75 GAA (0.41) MAPTKDM4EMEN1LMNAGAA
SCHEMBL29922719 0.75 MAPT (0.43) MAPTKDM4EMEN1LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3623398-B1 RESIN COMPOSITION COMPRISING A MODIFIED BLOCK COPOLYMER AND METHOD FOR PRODUCING MODIFIED BLOCK COPOLYMER ASAHI CHEMICAL IND (JP) 2024-08-28 EP disclosed
CN-110603273-B Modified block copolymer, method for producing modified block copolymer, and resin composition 旭化成株式会社 2022-10-14 CN disclosed
US-11124593-B2 Modified block copolymer, method for producing modified block copolymer, and resin composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2021-09-21 US disclosed
US-20200199282-A1 Modified Block Copolymer, Method for Producing Modified Block Copolymer, and Resin Composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2020-06-25 US disclosed
EP-3623398-A1 MODIFIED BLOCK COPOLYMER, METHOD FOR PRODUCING MODIFIED BLOCK COPOLYMER, AND RESIN COMPOSITION Asahi Kasei Kabushiki Kaisha (JP) 2020-03-18 EP disclosed