SCHEMBL21799861

SCHEMBL21799861

CC(Nc1ccc(N)cc1)C(C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLK1 P53350 3/20 0.40
CHEK1 O14757 2/20 0.38
CDC7 O00311 1/20 0.38
PLK4 O00444 1/20 0.38
DAPK3 O43293 1/20 0.38
ROCK2 O75116 1/20 0.38
CHEK2 O96017 1/20 0.38
PIM1 P11309 1/20 0.38
GSK3A P49840 1/20 0.38
GSK3B P49841 1/20 0.38
PRKX P51817 1/20 0.38
CSNK1G2 P78368 1/20 0.38
PRKCZ Q05513 1/20 0.38
ROCK1 Q13464 1/20 0.38
PKN2 Q16513 1/20 0.38
CDC42BPA Q5VT25 1/20 0.38
PLK3 Q9H4B4 1/20 0.38
CLK4 Q9HAZ1 1/20 0.38
MKNK2 Q9HBH9 1/20 0.38
CSNK1G1 Q9HCP0 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21799723 0.77 MAPT (0.39) MAPTALDH1A1CYP3A4L3MBTL1TDP1
SCHEMBL12957338 0.77 PLK1 (0.59) PLK1CHEK1CDC7PLK4DAPK3
SCHEMBL2958217 0.77 ALDH1A1 (0.40) PLK1CHEK1CDC7PLK4DAPK3
SCHEMBL475453 0.77 TDP1 (0.56) GSK3BMAPTALDH1A1CYP3A4L3MBTL1
SCHEMBL28349412 0.77 TDP1 (0.42) MAPTALDH1A1CYP3A4L3MBTL1TDP1
SCHEMBL21799928 0.76 MEN1 (0.46) PLK1MAPTALDH1A1CYP3A4TDP1
SCHEMBL29922411 0.76 MEN1 (0.46) PLK1MAPTALDH1A1CYP3A4TDP1
SCHEMBL31092472 0.75 ALDH1A1 (0.53) PLK1MAPTALDH1A1L3MBTL1TDP1
SCHEMBL8176841 0.75 CA1 (0.49) PLK1CHEK1CDC7PLK4DAPK3
Hydrogen Sulfide SCHEMBL8431365 0.75 TDP1 (0.54) GSK3BMAPTALDH1A1CYP3A4L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3623398-B1 RESIN COMPOSITION COMPRISING A MODIFIED BLOCK COPOLYMER AND METHOD FOR PRODUCING MODIFIED BLOCK COPOLYMER ASAHI CHEMICAL IND (JP) 2024-08-28 EP disclosed
CN-110603273-B Modified block copolymer, method for producing modified block copolymer, and resin composition 旭化成株式会社 2022-10-14 CN disclosed
US-11124593-B2 Modified block copolymer, method for producing modified block copolymer, and resin composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2021-09-21 US disclosed
US-20200199282-A1 Modified Block Copolymer, Method for Producing Modified Block Copolymer, and Resin Composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2020-06-25 US disclosed
EP-3623398-A1 MODIFIED BLOCK COPOLYMER, METHOD FOR PRODUCING MODIFIED BLOCK COPOLYMER, AND RESIN COMPOSITION Asahi Kasei Kabushiki Kaisha (JP) 2020-03-18 EP disclosed
CN-110603273-A Modified block copolymer, method for producing modified block copolymer, and resin composition 旭化成株式会社 2019-12-20 CN disclosed