Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PLK1 | P53350 | 3/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2971862 | 0.78 | TDP1 (0.54) | ALDH1A1SMN1; SMN2TDP1TSHRL3MBTL1 | |
| SCHEMBL21799861 | 0.77 | PLK1 (0.40) | ALDH1A1SMN1; SMN2TDP1TSHRL3MBTL1 | |
| SCHEMBL12957338 | 0.76 | PLK1 (0.59) | ALDH1A1TDP1TSHRL3MBTL1CYP3A4 | |
| SCHEMBL12192566 | 0.74 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2TDP1TSHRL3MBTL1 | |
| SCHEMBL16623692 | 0.74 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2TDP1TSHRL3MBTL1 | |
| SCHEMBL31092472 | 0.73 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2TDP1L3MBTL1THRB | |
| SCHEMBL8176841 | 0.73 | CA1 (0.49) | ALDH1A1LMNAHTTPLK1CHEK1 | |
| SCHEMBL48404 | 0.72 | ALDH1A1 (0.78) | ALDH1A1SMN1; SMN2TDP1TSHRL3MBTL1 | |
| SCHEMBL27314450 | 0.72 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2TDP1TSHRL3MBTL1 | |
| SCHEMBL15342891 | 0.72 | TDP1 (0.48) | ALDH1A1SMN1; SMN2TDP1TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8212078-B2 | Making chain extenders with slower cure rates; reacting a ketone and/or aldehyde with a primary amine in the presence of an acidic ion exchange resin and hydrogenation agent; making diimine same way but excluding hydrogenation agent; e.g. N,N'-di-5-nonyl-isophoronediamine | ALBEMARLE CORPORATION (US) | 2012-07-03 | — | — | US | disclosed |
| US-7767858-B2 | Diimines and secondary diamines | ALBEMARLE CORPORATION (US) | 2010-08-03 | — | — | US | disclosed |
| EP-2143707-A2 | Secondary diamine | Albermarle Corporation (US) | 2010-01-13 | — | — | EP | disclosed |
| US-20080315155-A1 | Diamines Having Reduced Color | ALBEMARLE CORPORATION (US) | 2008-12-25 | — | — | US | disclosed |
| US-20080262187-A1 | Blends of Diamines Having Reduced Color | ALBEMARLE CORPORATION (US) | 2008-10-23 | — | — | US | disclosed |
| EP-1966265-A2 | BLENDS OF DIAMINES HAVING REDUCED COLOR | Albermarle Corporation (US) | 2008-09-10 | — | — | EP | disclosed |
| US-20080194788-A1 | Diimines and Secondary Diamines | ALBEMARLE CORPORATION (US) | 2008-08-14 | — | — | US | disclosed |
| US-20080033210-A1 | DIIMINES AND SECONDARY DIAMINES | ALBEMARLE CORPORATION (US) | 2008-02-07 | — | — | US | disclosed |
| US-20080004406-A1 | DIIMINES AND SECONDARY DIAMINES | ALBEMARLE CORPORATION (US) | 2008-01-03 | — | — | US | disclosed |
| US-7288677-B2 | Diimines and secondary diamines | ALBEMARLE CORPORATION (US) | 2007-10-30 | — | — | US | disclosed |
| WO-2007079365-A2 | BLENDS OF DIAMINES HAVING REDUCED COLOR | ALBEMARLE CORPORATION (US) | 2007-07-12 | — | — | WO | disclosed |
| US-20060217567-A1 | Diimines and secondary diamines | ALBEMARLE CORPORATION | 2006-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080004406-A1 | DIIMINES AND SECONDARY DIAMINES | DDT, DDC, AOC1 | ALDH1A1 412/4885SMN1; SMN2 3151/4885TDP1 1225/4885 |
| US-20080262187-A1 | Blends of Diamines Having Reduced Color | DDT, DDC, AOC1 | ALDH1A1 181/4885SMN1; SMN2 1405/4885TDP1 483/4885 |
| US-20080033210-A1 | DIIMINES AND SECONDARY DIAMINES | DDT, DDC, AOC1 | ALDH1A1 412/4885SMN1; SMN2 3151/4885TDP1 1225/4885 |
| US-20080315155-A1 | Diamines Having Reduced Color | DDT, DPYD, DDC | ALDH1A1 213/4885SMN1; SMN2 1733/4885TDP1 486/4885 |
| US-20080194788-A1 | Diimines and Secondary Diamines | DDT, DDC, AOC1 | ALDH1A1 252/4885SMN1; SMN2 3047/4885TDP1 1248/4885 |
| US-20060217567-A1 | Diimines and secondary diamines | DDT, DDC, AOC1 | ALDH1A1 412/4885SMN1; SMN2 3151/4885TDP1 1225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.