Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | RECQL | P46063 | 1/20 | 0.66 |
| ▸ | PKM | P14618 | 2/20 | 0.61 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.61 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | SLC13A5 | Q86YT5 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21800666 | 0.94 | KMT2A (0.74) | GAAKMT2AMEN1RECQLPKM | |
| SCHEMBL21766071 | 0.91 | GAA (0.79) | GAAKMT2AMEN1RECQLPKM | |
| SCHEMBL20511868 | 0.90 | KMT2A (0.69) | GAAKMT2AMEN1RECQLPKM | |
| SCHEMBL21800694 | 0.86 | KMT2A (0.76) | GAAKMT2AMEN1RECQLPKM | |
| SCHEMBL21800631 | 0.86 | GAA (0.71) | GAAKMT2AMEN1RECQLPKM | |
| SCHEMBL21765927 | 0.83 | GAA (0.67) | GAAKMT2AMEN1RECQLPKM | |
| SCHEMBL21800573 | 0.83 | GAA (0.66) | GAAKMT2AMEN1RECQLPKM | |
| SCHEMBL21883498 | 0.82 | KMT2A (1.00) | GAAKMT2AMEN1RECQLPKM | |
| SCHEMBL20258829 | 0.81 | KMT2A (0.83) | GAAKMT2AMEN1RECQLPKM | |
| SCHEMBL20511829 | 0.80 | KMT2A (0.77) | GAAKMT2AMEN1RECQLPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200087258-A1 | INHIBITOR OF CITRATE TRANSPORTER AND THEIR USE IN THERAPY | ETERNYGEN GMBH (DE) | 2020-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200087258-A1 | INHIBITOR OF CITRATE TRANSPORTER AND THEIR USE IN THERAPY | CS, SLC2A1, SLC2A2 | GAA 108/4885KMT2A 1382/4885MEN1 3535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.