SCHEMBL21800941

SCHEMBL21800941

CS(=O)(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.69

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.69
CA2 P00918 1/20 0.69
HTR2A P28223 1/20 0.44
CASP3 P42574 3/20 0.42
KMT2A Q03164 2/20 0.41
FABP5 Q01469 3/20 0.40
FABP7 O15540 2/20 0.40
EPHX2 P34913 1/20 0.38
POLB P06746 1/20 0.38
GPR3 P46089 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3917763 0.78 HSD17B10 (0.48) CA1CA2POLB
SCHEMBL580310 0.77 CA1 (0.58) CA1CA2POLB
SCHEMBL15856770 0.75 CA1 (0.50) CA1CA2HTR2ACASP3KMT2A
SCHEMBL2063849 0.74 CA2 (0.39) CA1CA2KMT2APOLB
SCHEMBL31501939 0.74 CA1 (0.53) CA1CA2HTR2AKMT2AFABP5
SCHEMBL456018 0.74 CA1 (0.53) CA1CA2HTR2AKMT2AFABP5
SCHEMBL2730698 0.73 CA1 (0.57) CA1CA2HTR2AKMT2AFABP5
SCHEMBL21800942 0.71 CA1 (0.56) CA1CA2HTR2ACASP3KMT2A
SCHEMBL1275884 0.71 CA1 (0.50) CA1CA2HTR2AKMT2AFABP5
SCHEMBL3846181 0.71 CA1 (0.42) CA1CA2HTR2AKMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118561953-A Macrocyclic alkynyl thioether peptide compound and preparation method and application thereof 杭州市西溪医院 2024-08-30 CN disclosed
WO-2020054287-A1 PEPTIDE PURIFICATION METHOD USING SULFONATE COMPOUND 長瀬産業株式会社 2020-03-19 WO disclosed