SCHEMBL580310

SCHEMBL580310

Cc1ccc(S(=O)(=O)OCC2c3ccccc3-c3ccccc32)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.58
CA2 P00918 1/20 0.58
VDR P11473 2/20 0.48
ALDH1A1 P00352 6/20 0.42
HTR6 P50406 1/20 0.40
DHODH Q02127 1/20 0.40
MAPT P10636 3/20 0.40
LMNA P02545 2/20 0.40
USP2 O75604 1/20 0.40
POLB P06746 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
NOD2 Q9HC29 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
RECQL P46063 1/20 0.39
KDM4E B2RXH2 2/20 0.39
HPGD P15428 1/20 0.39
KEAP1 Q14145 1/20 0.38
NFE2L2 Q16236 1/20 0.38
FFAR4 Q5NUL3 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9211778 0.87 CA1 (0.42) CA1CA2VDRALDH1A1HTR6
SCHEMBL6004127 0.85 VDR (0.46) CA1CA2VDRALDH1A1HTR6
SCHEMBL8587365 0.81 CA1 (0.54) CA1CA2MAPTPOLBCYP2C19
SCHEMBL21800941 0.77 CA1 (0.69) CA1CA2POLB
SCHEMBL9213914 0.77 ALDH1A1 (0.39) CA1CA2VDRALDH1A1HTR6
SCHEMBL8639499 0.77 ALDH1A1 (0.43) VDRALDH1A1HTR6MAPTLMNA
SCHEMBL9205983 0.76 HTR2A (0.39) CA1CA2ALDH1A1MAPTLMNA
SCHEMBL7723181 0.75 ALDH1A1 (0.48) CA1CA2ALDH1A1HTR6MAPT
SCHEMBL20649637 0.75 KMT2A (0.48) CA1CA2ALDH1A1LMNARECQL
SCHEMBL29839653 0.74 KMT2A (0.53) CA1CA2ALDH1A1LMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10787576-B2 Method for the preparation of a coating comprising oligomeric alkynes ÉCOLE POLYTECHNIQUE FÉDÉRALE DE LAUSANNE (EPFL) EPFL-TTO (CH) 2020-09-29 US disclosed
US-20190048202-A1 METHOD FOR THE PREPARATION OF A COATING COMPRISING OLIGOMERIC ALKYNES ÉCOLE POLYTECHNIQUE FÉDÉRALE DE LAUSANNE (EPFL) EPFL-TTO (CH) 2019-02-14 US disclosed
US-20180171152-A1 METHOD FOR THE PREPARATION OF A COATING ÉCOLE POLYTECHNIQUE FÉDÉRALE DE LAUSANNE (EPFL) EPFL-TTO (CH) 2018-06-21 US disclosed
EP-3303482-A1 METHOD FOR THE PREPARATION OF A COATING Ecole Polytechnique Fédérale de Lausanne (EPFL) EPFL-TTO (CH) 2018-04-11 EP disclosed
WO-2016189047-A1 METHOD FOR THE PREPARATION OF A COATING ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) EPFL-TTO (CH) 2016-12-01 WO disclosed
WO-2016174266-A2 METHOD FOR THE PREPARATION OF A COATING ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) EPFL-TTO (CH) 2016-11-03 WO disclosed
EP-3053914-A1 FLUOROPHORE AND FLUORESCENT SENSOR COMPOUND CONTAINING SAME LIGHTSHIP MEDICAL LIMITED (GB) 2016-08-10 EP disclosed
EP-2417102-B1 FLUOROPHORE AND FLUORESCENT SENSOR COMPOUND CONTAINING SAME LIGHTSHIP MEDICAL LTD (GB) 2016-04-06 EP disclosed
US-20160033521-A1 FLUOROPHORE AND FLUORESCENT SENSOR COMPOUND CONTAINING SAME LIGHTSHIP MEDICAL LIMITED (GB) 2016-02-04 US disclosed
US-9115063-B2 Fluorophore and fluorescent sensor compound containing same LIGHTSHIP MEDICAL LIMITED (GB) 2015-08-25 US disclosed
US-20120156793-A1 FLUOROPHORE AND FLUORESCENT SENSOR COMPOUND CONTAINING SAME LIGHTSHIP MEDICAL LIMITED (GB) 2012-06-21 US disclosed
EP-2417102-A2 FLUOROPHORE AND FLUORESCENT SENSOR COMPOUND CONTAINING SAME Glysure Ltd (GB) 2012-02-15 EP disclosed
WO-2010116142-A2 FLUOROPHORE AND FLUORESCENT SENSOR COMPOUND CONTAINING SAME GLYSURE LTD (GB) 2010-10-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160033521-A1 FLUOROPHORE AND FLUORESCENT SENSOR COMPOUND CONTAINING SAME QRFPR, TRPA1, GPR52 CA1 2604/4885CA2 1151/4885VDR 709/4885
US-20120156793-A1 FLUOROPHORE AND FLUORESCENT SENSOR COMPOUND CONTAINING SAME QRFPR, TRPA1, GPR52 CA1 2776/4885CA2 1195/4885VDR 731/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.