Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | CCNC | P24863 | 1/20 | 0.31 |
| ▸ | CDK8 | P49336 | 1/20 | 0.31 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.30 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.30 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.30 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3680598 | 0.77 | MAPT (0.40) | SLC22A12KDM4EMAPTHTTSMN1; SMN2 | |
| SCHEMBL4051088 | 0.77 | PARP1 (0.39) | AXLCCNCCDK8 | |
| SCHEMBL29890100 | 0.75 | AXL (0.72) | AXLSLC22A12CCNCCDK8IMPDH2 | |
| SCHEMBL244397 | 0.75 | AXL (0.72) | AXLSLC22A12CCNCCDK8IMPDH2 | |
| SCHEMBL29566353 | 0.74 | AXL (0.50) | AXLERN1SLC22A12CCNCCDK8 | |
| SCHEMBL1034122 | 0.74 | AXL (0.50) | AXLERN1SLC22A12CCNCCDK8 | |
| SCHEMBL29954490 | 0.71 | CYP3A4 (0.49) | ERN1KDM4EHTTSMN1; SMN2MAPK8 | |
| SCHEMBL14893841 | 0.71 | TNF (0.45) | KDM4EHTTSMN1; SMN2MAPK8MAPK9 | |
| SCHEMBL1828134 | 0.71 | CYP3A4 (0.49) | ERN1KDM4EHTTSMN1; SMN2MAPK8 | |
| SCHEMBL26933223 | 0.70 | AXL (0.55) | AXLSLC22A12IMPDH2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3849973-A1 | ISOXAZOLINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | FMC Corporation (US) | 2021-07-21 | — | — | EP | disclosed |
| WO-2020055955-A1 | ISOXAZOLINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | FMC CORPORATION (US) | 2020-03-19 | — | — | WO | disclosed |