Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.72 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.39 |
| ▸ | CHUK | O15111 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 2/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | PRKCI | P41743 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29890100 | 1.00 | AXL (0.72) | AXLIMPDH2EP300KAT2BKAT8 | |
| SCHEMBL17558948 | 0.84 | AXL (0.55) | AXLIMPDH2EP300KAT2BKAT8 | |
| SCHEMBL22787692 | 0.84 | AXL (0.55) | AXLIMPDH2EP300KAT2BKAT8 | |
| SCHEMBL3362445 | 0.84 | EP300 (0.60) | AXLIMPDH2EP300KAT2BKAT8 | |
| SCHEMBL12245721 | 0.84 | AXL (0.60) | AXLIMPDH2EP300KAT2BKAT8 | |
| SCHEMBL24724775 | 0.84 | AXL (0.55) | AXLIMPDH2EP300KAT2BKAT8 | |
| SCHEMBL12957492 | 0.84 | AXL (0.55) | AXLIMPDH2EP300KAT2BKAT8 | |
| SCHEMBL21917158 | 0.84 | AXL (0.60) | AXLIMPDH2EP300KAT2BKAT8 | |
| SCHEMBL4021511 | 0.84 | AXL (0.85) | AXLIMPDH2EP300KAT2BKAT8 | |
| SCHEMBL246823 | 0.84 | AXL (1.00) | AXLIMPDH2EP300KAT2BKAT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115161016-B | Sensor for detecting kaempferol and quercetin in tobacco leaves and preparation method thereof | 云南省烟草质量监督检测站 | 2024-04-30 | — | — | CN | claimed |
| CN-115161016-A | Sensor for detecting kaempferol and quercetin in tobacco leaves and preparation method thereof | 云南省烟草质量监督检测站 | 2022-10-11 | — | — | CN | claimed |
| CN-110669546-A | Catalytic slurry oil filtering device and method suitable for long-period operation | 上海蓝科石化环保科技股份有限公司 | 2020-01-10 | — | — | CN | claimed |
| US-10125226-B2 | Scale-up process of bifunctionalized triblock copolymers with secondary and tertiary amines, with application in dewatering and desalting of heavy crude oils | INSTITUTO MEXICANO DEL PETROLEO (MX) | 2018-11-13 | — | — | US | claimed |
| US-20140364566-A1 | SCALE-UP PROCESS OF BIFUNCTIONALIZED TRIBLOCK COPOLYMERS WITH SECONDARY AND TERTIARY AMINES, WITH APPLICATION IN DEWATERING AND DESALTING OF HEAVY CRUDE OILS | INSTITUTO MEXICANO DEL PETROLEO (MX) | 2014-12-11 | — | — | US | claimed |
| US-12435040-B2 | 1,3-substituted cyclobutyl derivatives and uses thereof | BAUSCH + LOMB IRELAND LIMITED (IE) | 2025-10-07 | — | — | US | disclosed |
| EP-3873605-B1 | COMPOUNDS FOR INHIBITION OF ALPHA4BETA7 INTEGRIN | GILEAD SCIENCES INC (US) | 2024-10-23 | — | — | EP | disclosed |
| US-20240308965-A1 | 1,3-SUBSTITUTED CYCLOBUTYL DERIVATIVES AND USES THEREOF | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR AGENT | 2024-09-19 | — | — | US | disclosed |
| CN-115161016-B | Sensor for detecting kaempferol and quercetin in tobacco leaves and preparation method thereof | 云南省烟草质量监督检测站 | 2024-04-30 | — | — | CN | disclosed |
| CN-112969504-B | Compounds for inhibiting alpha 4 beta 7 integrin | 吉利德科学公司 | 2024-04-09 | — | — | CN | disclosed |
| EP-4313951-A1 | 1,3-SUBSTITUTED CYCLOBUTYL DERIVATIVES AND USES THEREOF | Novartis AG (CH) | 2024-02-07 | — | — | EP | disclosed |
| US-11845730-B2 | 1,3-substituted cyclobutyl derivatives and uses thereof | CITIBANK, N.A., AS NOTES COLLATERAL AGENT | 2023-12-19 | — | — | US | disclosed |
| WO-2007079162-A1 | ISOXAZOLINES FOR CONTROLLING INVERTEBRATE PESTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-07-12 | — | — | WO | disclosed |
| WO-2007079162-A1 | ISOXAZOLINES FOR CONTROLLING INVERTEBRATE PESTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-07-12 | — | — | WO | disclosed |
| EP-1089976-B1 | METHOD OF PREPARING 5- OR 8-BROMOISOQUINOLINE DERIVATIVES | NEUROSEARCH AS (DK) | 2003-09-24 | — | — | EP | disclosed |
| US-6500954-B1 | ONE POT PROCESS OF BROMINATION AND NITRATION OF ISOQUINOLINE TO PRODUCE SUCH AS 5-BROMO-8-NITROISOQUINOLINE | NEUROSEARCH A/S (DK) | 2002-12-31 | — | — | US | disclosed |
| EP-1089976-A1 | METHOD OF PREPARING 5- OR 8-BROMOISOQUINOLINE DERIVATIVES | NEUROSEARCH A/S (DK) | 2001-04-11 | — | — | EP | disclosed |
| WO-1999067218-A2 | METHOD OF PREPARING 5- OR 8-BROMOISOQUINOLINE DERIVATIVES | NEUROSEARCH A/S (DK) | 1999-12-29 | — | — | WO | disclosed |
| US-5367038-A | Polyisoquinolinediyls and uses thereof | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 1994-11-22 | — | — | US | disclosed |
| US-5244992-A | Poly(iso)quinolinediyls and preparation and use thereof | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 1993-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11845730-B2 | 1,3-substituted cyclobutyl derivatives and uses thereof | TRPV1, TRPV3, TRPV2 | AXL 2928/4885IMPDH2 3733/4885EP300 3368/4885 |
| US-12435040-B2 | 1,3-substituted cyclobutyl derivatives and uses thereof | TRPV1, TRPV3, TRPV2 | AXL 2928/4885IMPDH2 3733/4885EP300 3368/4885 |
| US-20240308965-A1 | 1,3-SUBSTITUTED CYCLOBUTYL DERIVATIVES AND USES THEREOF | TRPV1, TRPV3, TRPV2 | AXL 2928/4885IMPDH2 3733/4885EP300 3368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.