Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 8/20 | 0.53 |
| ▸ | CCNE1 | P24864 | 8/20 | 0.53 |
| ▸ | CDK2 | P24941 | 8/20 | 0.53 |
| ▸ | DBF4 | Q9UBU7 | 8/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | QPCT | Q16769 | 1/20 | 0.47 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.46 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.43 |
| ▸ | ATP4A | P20648 | 1/20 | 0.41 |
| ▸ | ATP4B | P51164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21801474 | 0.89 | NPC1 (0.46) | CDC7CCNE1CDK2DBF4KDM4E | |
| SCHEMBL21801697 | 0.82 | RAB9A (0.51) | KDM4EALDH1A1MEN1NPC1LMNA | |
| SCHEMBL21801500 | 0.77 | CDC7 (0.50) | CDC7CCNE1CDK2DBF4QPCT | |
| SCHEMBL21801526 | 0.75 | CDC7 (0.48) | CDC7CCNE1CDK2DBF4QPCT | |
| SCHEMBL5103657 | 0.75 | CDC25B (0.52) | KDM4EALDH1A1MEN1NPC1LMNA | |
| SCHEMBL21801541 | 0.74 | QPCT (0.47) | KDM4EALDH1A1MEN1NPC1LMNA | |
| SCHEMBL16157018 | 0.70 | CDC7 (0.61) | CDC7CCNE1CDK2DBF4KDM4E | |
| SCHEMBL12506933 | 0.69 | CDK2 (1.00) | CDC7CCNE1CDK2DBF4QPCT | |
| SCHEMBL20508261 | 0.68 | RAB9A (0.55) | ALDH1A1NPC1RAB9ASMN1; SMN2EGFR | |
| SCHEMBL13700955 | 0.68 | KDM4E (0.54) | KDM4EALDH1A1MEN1NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220257569-A1 | INDOLE-OXADIAZOLE COMPOUNDS AND THEIR THERAPEUTIC USE | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2022-08-18 | — | — | US | disclosed |
| WO-2020051707-A1 | INDOLE-OXADIAZOLE COMPOUNDS AND THEIR THERAPEUTIC USE | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2020-03-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220257569-A1 | INDOLE-OXADIAZOLE COMPOUNDS AND THEIR THERAPEUTIC USE | CNR2, GPR119, CNR1 | CDC7 4106/4885CCNE1 3200/4885CDK2 1204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.