SCHEMBL21804428

SCHEMBL21804428

CCC#CCn1ccnc1-c1ncc[nH]1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NISCH Q9Y2I1 2/20 0.39
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP19A1 P11511 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
CHRM2 P08172 2/20 0.36
CHRM5 P08912 2/20 0.36
CHRM1 P11229 2/20 0.36
MTOR P42345 1/20 0.34
ADK P55263 1/20 0.34
ALDH1A1 P00352 4/20 0.33
KDM4E B2RXH2 1/20 0.33
KCNK13 Q9HB14 1/20 0.33
BRD4 O60885 1/20 0.32
KMT2A Q03164 2/20 0.32
POLB P06746 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
ADORA2A P29274 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28796695 0.81 NISCH (0.40) NISCHCYP1A2CYP3A4CYP2D6CYP19A1
SCHEMBL11011484 0.72 NISCH (0.38) NISCHCYP1A2CYP3A4CYP2D6CYP19A1
SCHEMBL5047485 0.70 NISCH (0.36) NISCHCYP1A2CYP3A4CYP2D6CYP19A1
SCHEMBL6017638 0.70 NISCH (0.38) NISCHCYP1A2CYP3A4CYP2D6CYP19A1
SCHEMBL9369328 0.70 HSD17B10 (0.55) NISCHCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL3534451 0.69 BRD4 (0.46) NISCHCYP1A2CYP3A4CYP2D6CYP19A1
SCHEMBL9373068 0.68 CYP1A2 (0.45) CYP1A2CYP2D6CYP2C19ALDH1A1KDM4E
SCHEMBL13296403 0.67 SMN1; SMN2 (0.46) CYP2D6CYP2C19CHRM2CHRM5CHRM1
SCHEMBL9369730 0.67 CYP2D6 (0.36) NISCHCYP3A4CYP2D6CYP2C9MTOR
SCHEMBL9369845 0.66 HSP90AA1 (0.37) NISCHMTORADKKCNK13BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020059997-A1 OXIDATION-REDUCTION POLYMER INCLUDING TRANSITION METAL COMPLEX, AND ELECTROCHEMICAL BIOSENSOR USING SAME 주식회사 아이센스 2020-03-26 WO disclosed